CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome

Abstract Background This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-...

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Main Authors: Ibrahim A. I. Mohamed, Hosam A. Hasan, Mohamed Abdel-Tawab
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:https://doi.org/10.1186/s43055-020-00385-x
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author Ibrahim A. I. Mohamed
Hosam A. Hasan
Mohamed Abdel-Tawab
author_facet Ibrahim A. I. Mohamed
Hosam A. Hasan
Mohamed Abdel-Tawab
author_sort Ibrahim A. I. Mohamed
collection DOAJ
description Abstract Background This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-19 patients during April 2020. The chest CT and laboratory data were analyzed. The primary endpoint was patient survival either died or survived. The relationship between CT and laboratory findings was correlated to patient outcome. Results The study group included 164 patients (86 male, 78 women; average age, 44.3 ± 16.5 years) whose RT-PCR were positive for COVID-19. Only 120 (73.2%) patients had pulmonary manifestations. Ground glass opacities of peripheral distribution and multifocal affection were the major CT finding in COVID-19 patients. Univariate analysis revealed that CT severity score, D-dimer level, age, total leucocytic count, and absolute lymphocytic count were predictive for death. Conclusion CT has an emerging role in the diagnosis of COVID-19 pneumonia and in assessing disease severity. CT severity score, D-dimer, total leucocytic count, and absolute lymphocytic count significantly predict patient survival.
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spelling doaj.art-06e6a2ede7af4f219a86b266e17185992022-12-21T17:13:10ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622021-01-015211710.1186/s43055-020-00385-xCT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcomeIbrahim A. I. Mohamed0Hosam A. Hasan1Mohamed Abdel-Tawab2Department of Diagnostic Radiology, Assiut UniversityDepartment of Diagnostic Radiology, Assiut UniversityDepartment of Diagnostic Radiology, Assiut UniversityAbstract Background This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-19 patients during April 2020. The chest CT and laboratory data were analyzed. The primary endpoint was patient survival either died or survived. The relationship between CT and laboratory findings was correlated to patient outcome. Results The study group included 164 patients (86 male, 78 women; average age, 44.3 ± 16.5 years) whose RT-PCR were positive for COVID-19. Only 120 (73.2%) patients had pulmonary manifestations. Ground glass opacities of peripheral distribution and multifocal affection were the major CT finding in COVID-19 patients. Univariate analysis revealed that CT severity score, D-dimer level, age, total leucocytic count, and absolute lymphocytic count were predictive for death. Conclusion CT has an emerging role in the diagnosis of COVID-19 pneumonia and in assessing disease severity. CT severity score, D-dimer, total leucocytic count, and absolute lymphocytic count significantly predict patient survival.https://doi.org/10.1186/s43055-020-00385-xCOVID-19Viral pneumoniaGround-glass opacities, D-dimer
spellingShingle Ibrahim A. I. Mohamed
Hosam A. Hasan
Mohamed Abdel-Tawab
CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
The Egyptian Journal of Radiology and Nuclear Medicine
COVID-19
Viral pneumonia
Ground-glass opacities, D-dimer
title CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_full CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_fullStr CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_full_unstemmed CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_short CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_sort ct characteristics and laboratory findings of covid 19 pneumonia in relation to patient outcome
topic COVID-19
Viral pneumonia
Ground-glass opacities, D-dimer
url https://doi.org/10.1186/s43055-020-00385-x
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