Regulatory T Cell (Treg) Cytotoxic T Lymphocyte–associated Antigen-4 Deficits in Biliary Atresia (BA) and Disease Rescue With Treg Augmentation in Murine BA

Regulatory T Cell (Treg) Cytotoxic T Lymphocyte–associated Antigen-4 Deficits in Biliary Atresia (BA) and Disease Rescue With Treg Augmentation in Murine BA

Background and Aims: Biliary atresia (BA) entails an inflammatory injury of the biliary tree, leading to fibrosis of the extrahepatic and intrahepatic bile ducts. The chronic inflammatory biliary injury may be due to lack of appropriate regulatory T cell (Treg) suppression of inflammation. The aims...

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Bibliographic Details
Main Authors: Yuhuan Luo, Joseph Bednarek, Alexander Chaidez, Shaikh Atif, Dong Wang, Cara L. Mack
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Gastro Hep Advances
Subjects:
Bile Duct
Children
Cholestasis
Cytotoxic T Lymphocyte–associated Antigen-4
Forkhead Box P3
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322000097

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