Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview
Amyotrophic lateral sclerosis (ALS) represents a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord leading to the impairment of volun-tary muscle control and eventually death. It accounts for about 80%-90% of all motor neu-ron diseases, and is characterize...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Romanian Association of Balneology, Editura Balneara
2023-06-01
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| Series: | Balneo and PRM Research Journal |
| Subjects: | |
| Online Access: | http://bioclima.ro/Balneo559.pdf |
| _version_ | 1797786817954578432 |
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| author | Silvina Iluț Adina Stan Imelda Rahovan Elian Hapca Ioana Zmaranda Stefan Strilciuc Dafin Muresanu |
| author_facet | Silvina Iluț Adina Stan Imelda Rahovan Elian Hapca Ioana Zmaranda Stefan Strilciuc Dafin Muresanu |
| author_sort | Silvina Iluț |
| collection | DOAJ |
| description | Amyotrophic lateral sclerosis (ALS) represents a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord leading to the impairment of volun-tary muscle control and eventually death. It accounts for about 80%-90% of all motor neu-ron diseases, and is characterized by a marked variability in terms of clinical forms, gene-tics, survival rate and diagnostic particularities. A diagnosis of ALS or one of the variants comes with a great burden for the patient and patient’s family because of the high morbidi-ty and mortality rate of this disorder. As a consequence, it is mandatory to optimize the ac-curacy of the diagnostic process of ALS spectrum for providing the best clinical manage-ment and quality of life for patients and avoiding diagnostic mistakes. Our review focuses on the general and particular aspects of ALS and its variants in an effort to improve the process of diagnosis, therapy and exclusion of mimics of this group of diseases and to pro-vide the latest findings in this field. |
| first_indexed | 2024-03-13T01:14:13Z |
| format | Article |
| id | doaj.art-06ecb5dfee1a417e99405a3daccdefc6 |
| institution | Directory Open Access Journal |
| issn | 2734-8458 |
| language | English |
| last_indexed | 2024-03-13T01:14:13Z |
| publishDate | 2023-06-01 |
| publisher | Romanian Association of Balneology, Editura Balneara |
| record_format | Article |
| series | Balneo and PRM Research Journal |
| spelling | doaj.art-06ecb5dfee1a417e99405a3daccdefc62023-07-05T13:24:51ZengRomanian Association of Balneology, Editura BalnearaBalneo and PRM Research Journal2734-84582023-06-0114255910.12680/balneo.2023.559Variants of Amyotrophic lateral sclerosis and rehabilitation: an overviewSilvina Iluț0Adina Stan1Imelda Rahovan2Elian Hapca3Ioana Zmaranda4Stefan Strilciuc5Dafin Muresanu61. Department of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaDepartment of Neuroscience, University of Medicine and Pharmacy “Iuliu Hațieganu” Cluj-Napoca; RomaniaAmyotrophic lateral sclerosis (ALS) represents a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord leading to the impairment of volun-tary muscle control and eventually death. It accounts for about 80%-90% of all motor neu-ron diseases, and is characterized by a marked variability in terms of clinical forms, gene-tics, survival rate and diagnostic particularities. A diagnosis of ALS or one of the variants comes with a great burden for the patient and patient’s family because of the high morbidi-ty and mortality rate of this disorder. As a consequence, it is mandatory to optimize the ac-curacy of the diagnostic process of ALS spectrum for providing the best clinical manage-ment and quality of life for patients and avoiding diagnostic mistakes. Our review focuses on the general and particular aspects of ALS and its variants in an effort to improve the process of diagnosis, therapy and exclusion of mimics of this group of diseases and to pro-vide the latest findings in this field.http://bioclima.ro/Balneo559.pdfmyotrophic lateral sclerosisrehabilitation in alsflail legflail armprogressive muscular atrophy |
| spellingShingle | Silvina Iluț Adina Stan Imelda Rahovan Elian Hapca Ioana Zmaranda Stefan Strilciuc Dafin Muresanu Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview Balneo and PRM Research Journal myotrophic lateral sclerosis rehabilitation in als flail leg flail arm progressive muscular atrophy |
| title | Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview |
| title_full | Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview |
| title_fullStr | Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview |
| title_full_unstemmed | Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview |
| title_short | Variants of Amyotrophic lateral sclerosis and rehabilitation: an overview |
| title_sort | variants of amyotrophic lateral sclerosis and rehabilitation an overview |
| topic | myotrophic lateral sclerosis rehabilitation in als flail leg flail arm progressive muscular atrophy |
| url | http://bioclima.ro/Balneo559.pdf |
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