An epidemic of dengue-1 in a remote village in rural Laos.
In the Lao PDR (Laos), urban dengue is an increasingly recognised public health problem. We describe a dengue-1 virus outbreak in a rural northwestern Lao forest village during the cool season of 2008. The isolated strain was genotypically "endemic" and not "sylvatic," belonging...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS Neglected Tropical Diseases |
| Online Access: | http://europepmc.org/articles/PMC3738459?pdf=render |
| _version_ | 1818150846818418688 |
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| author | Audrey Dubot-Pérès Phengta Vongphrachanh Justin Denny Rattanaphone Phetsouvanh Singharath Linthavong Bounthanom Sengkeopraseuth Amphai Khasing Vimattha Xaythideth Catrin E Moore Manivanh Vongsouvath Josée Castonguay-Vanier Bountoy Sibounheuang Thaksinaporn Taojaikong Anisone Chanthongthip Xavier de Lamballerie Paul N Newton |
| author_facet | Audrey Dubot-Pérès Phengta Vongphrachanh Justin Denny Rattanaphone Phetsouvanh Singharath Linthavong Bounthanom Sengkeopraseuth Amphai Khasing Vimattha Xaythideth Catrin E Moore Manivanh Vongsouvath Josée Castonguay-Vanier Bountoy Sibounheuang Thaksinaporn Taojaikong Anisone Chanthongthip Xavier de Lamballerie Paul N Newton |
| author_sort | Audrey Dubot-Pérès |
| collection | DOAJ |
| description | In the Lao PDR (Laos), urban dengue is an increasingly recognised public health problem. We describe a dengue-1 virus outbreak in a rural northwestern Lao forest village during the cool season of 2008. The isolated strain was genotypically "endemic" and not "sylvatic," belonging to the genotype 1, Asia 3 clade. Phylogenetic analyses of 37 other dengue-1 sequences from diverse areas of Laos between 2007 and 2010 showed that the geographic distribution of some strains remained focal overtime while others were dispersed throughout the country. Evidence that dengue viruses have broad circulation in the region, crossing country borders, was also obtained. Whether the outbreak arose from dengue importation from an urban centre into a dengue-naïve community or crossed into the village from a forest cycle is unknown. More epidemiological and entomological investigations are required to understand dengue epidemiology and the importance of rural and forest dengue dynamics in Laos. |
| first_indexed | 2024-12-11T13:29:25Z |
| format | Article |
| id | doaj.art-06ece4804aff450ca68dd5d2b1e8341d |
| institution | Directory Open Access Journal |
| issn | 1935-2727 1935-2735 |
| language | English |
| last_indexed | 2024-12-11T13:29:25Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Neglected Tropical Diseases |
| spelling | doaj.art-06ece4804aff450ca68dd5d2b1e8341d2022-12-22T01:05:21ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352013-01-0178e236010.1371/journal.pntd.0002360An epidemic of dengue-1 in a remote village in rural Laos.Audrey Dubot-PérèsPhengta VongphrachanhJustin DennyRattanaphone PhetsouvanhSingharath LinthavongBounthanom SengkeopraseuthAmphai KhasingVimattha XaythidethCatrin E MooreManivanh VongsouvathJosée Castonguay-VanierBountoy SibounheuangThaksinaporn TaojaikongAnisone ChanthongthipXavier de LamballeriePaul N NewtonIn the Lao PDR (Laos), urban dengue is an increasingly recognised public health problem. We describe a dengue-1 virus outbreak in a rural northwestern Lao forest village during the cool season of 2008. The isolated strain was genotypically "endemic" and not "sylvatic," belonging to the genotype 1, Asia 3 clade. Phylogenetic analyses of 37 other dengue-1 sequences from diverse areas of Laos between 2007 and 2010 showed that the geographic distribution of some strains remained focal overtime while others were dispersed throughout the country. Evidence that dengue viruses have broad circulation in the region, crossing country borders, was also obtained. Whether the outbreak arose from dengue importation from an urban centre into a dengue-naïve community or crossed into the village from a forest cycle is unknown. More epidemiological and entomological investigations are required to understand dengue epidemiology and the importance of rural and forest dengue dynamics in Laos.http://europepmc.org/articles/PMC3738459?pdf=render |
| spellingShingle | Audrey Dubot-Pérès Phengta Vongphrachanh Justin Denny Rattanaphone Phetsouvanh Singharath Linthavong Bounthanom Sengkeopraseuth Amphai Khasing Vimattha Xaythideth Catrin E Moore Manivanh Vongsouvath Josée Castonguay-Vanier Bountoy Sibounheuang Thaksinaporn Taojaikong Anisone Chanthongthip Xavier de Lamballerie Paul N Newton An epidemic of dengue-1 in a remote village in rural Laos. PLoS Neglected Tropical Diseases |
| title | An epidemic of dengue-1 in a remote village in rural Laos. |
| title_full | An epidemic of dengue-1 in a remote village in rural Laos. |
| title_fullStr | An epidemic of dengue-1 in a remote village in rural Laos. |
| title_full_unstemmed | An epidemic of dengue-1 in a remote village in rural Laos. |
| title_short | An epidemic of dengue-1 in a remote village in rural Laos. |
| title_sort | epidemic of dengue 1 in a remote village in rural laos |
| url | http://europepmc.org/articles/PMC3738459?pdf=render |
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