TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides

TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides

Tumor necrosis factor alpha (TNFα) is a pluripotent cytokine that is important in many infections, though its role in Coccidioides infection remains poorly understood. The need to understand TNFα in Coccidioides infection has increased recently with the widespread use of TNFα inhibitors for a wide v...

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Bibliographic Details
Main Authors: Daniel A. Powell, Lisa F. Shubitz, Christine D. Butkiewicz, Hien T. Trinh, Fariba M. Donovan, Jeffrey A. Frelinger, John N. Galgiani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Coccidioides
valley fever
TNFα
biological response modifiers
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.796114/full

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