Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosusResearch in context

Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosusResearch in context

Summary: Background: Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease affecting multiple organs and tissues with high cellular heterogeneity. CD8+ T cell activity is involved in the SLE pathogenesis. However, the cellular heterogeneity and the underlying mechanisms of CD8+ T...

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Bibliographic Details
Main Authors: Hui Xiong, Mintian Cui, Ni Kong, Jiongjie Jing, Ying Xu, Xiuting Liu, Fan Yang, Zhen Xu, Yu Yan, Dongyang Zhao, Ziqi Zou, Meng Xia, Junjie Cen, Guozhen Tan, Cong Huai, Qiong Fu, Qing Guo, Kun Chen
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
Systemic lupus erythematosus
scRNA-seq
Whole-exome sequencing
CD8+ T cell subset
Genetic variant
DTHD1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000725

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