Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants
Background and Purpose: However, little is known about the cardiac autonomic activity due to chemicals in psychiatric patients. Therefore, the objective of this study was to assess the effect of chemical irritants on the ANS of the person and measure that in the form of Heart Rate Variability (H...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2015-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6022/12896_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1819117897771909120 |
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| author | Priyanka Srivastava Supriya Gupta Rajesh Rastogi Manushree Gupta |
| author_facet | Priyanka Srivastava Supriya Gupta Rajesh Rastogi Manushree Gupta |
| author_sort | Priyanka Srivastava |
| collection | DOAJ |
| description | Background and Purpose: However, little is known about
the cardiac autonomic activity due to chemicals in psychiatric
patients. Therefore, the objective of this study was to assess
the effect of chemical irritants on the ANS of the person and
measure that in the form of Heart Rate Variability (HRV), a
noninvasive method to estimate the cardiac autonomic activity.
The autonomic nervous system can significantly compromised
by use of chemical irritants.
Materials and Methods: A cross-sectional hospital based study
was conducted in which 33 patients (mean age: 29.94 years)
of depression/anxiety were compared with 37 age matched
controls (mean age: 28.10). The patients who were diagnosed
as either depressed or anxious by the psychiatry were included
in the study group by random sampling. Out of these 8 patients
gave positive history of odour use. Thirty seven age matched
healthy persons were taken as controls. Grading of patients
was done according to DSMV-IV criteria and short- term HRV
was recorded. Five minute HRV recording was done and time
domain and frequency domain indices of HRV were assessed
using RMS Polyearite D. The result in case and control groups
was compared.
Results: We have reported a poor HRV compared to control
group in patients of depression/anxiety as reflected by NN50
values (p< 0.05). Although not significant the trend shows a
better HRV control in almost all the time domain and frequency
domain parameters in controls compared to cases. Regarding
the history of use of chemical irritants the trend showed a poor
HRV control in these cases compared to the patients who did
not give any such history.
Conclusion: Our results suggest that impaired cardiac
autonomic nerve function characterized by sympathetic over
activity may occur in depression/phobic patients. The study
also proves a poor HRV in psychiatric subjects with history of
use of odoriferous substances. |
| first_indexed | 2024-12-22T05:40:17Z |
| format | Article |
| id | doaj.art-06ef186a97eb42308799e6e9e835702b |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T05:40:17Z |
| publishDate | 2015-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-06ef186a97eb42308799e6e9e835702b2022-12-21T18:37:13ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196VC01VC0410.7860/JCDR/2015/12896.6022Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical IrritantsPriyanka Srivastava0Supriya Gupta1Rajesh Rastogi2Manushree Gupta3Assistant Professor, Department of Physiology, PGIMER and Dr. R.M.L Hospital, New Delhi, India.Professor, Department of Physiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.Consultant and Head, Department of Psychiatry, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.Assistant Professor, Department of Psychiatry, G.B.Pant and Maulana Azad Medical College, New Delhi, India.Background and Purpose: However, little is known about the cardiac autonomic activity due to chemicals in psychiatric patients. Therefore, the objective of this study was to assess the effect of chemical irritants on the ANS of the person and measure that in the form of Heart Rate Variability (HRV), a noninvasive method to estimate the cardiac autonomic activity. The autonomic nervous system can significantly compromised by use of chemical irritants. Materials and Methods: A cross-sectional hospital based study was conducted in which 33 patients (mean age: 29.94 years) of depression/anxiety were compared with 37 age matched controls (mean age: 28.10). The patients who were diagnosed as either depressed or anxious by the psychiatry were included in the study group by random sampling. Out of these 8 patients gave positive history of odour use. Thirty seven age matched healthy persons were taken as controls. Grading of patients was done according to DSMV-IV criteria and short- term HRV was recorded. Five minute HRV recording was done and time domain and frequency domain indices of HRV were assessed using RMS Polyearite D. The result in case and control groups was compared. Results: We have reported a poor HRV compared to control group in patients of depression/anxiety as reflected by NN50 values (p< 0.05). Although not significant the trend shows a better HRV control in almost all the time domain and frequency domain parameters in controls compared to cases. Regarding the history of use of chemical irritants the trend showed a poor HRV control in these cases compared to the patients who did not give any such history. Conclusion: Our results suggest that impaired cardiac autonomic nerve function characterized by sympathetic over activity may occur in depression/phobic patients. The study also proves a poor HRV in psychiatric subjects with history of use of odoriferous substances.https://jcdr.net/articles/PDF/6022/12896_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdfchemicalsdepressiondsmv ivphobia |
| spellingShingle | Priyanka Srivastava Supriya Gupta Rajesh Rastogi Manushree Gupta Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants Journal of Clinical and Diagnostic Research chemicals depression dsmv iv phobia |
| title | Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants |
| title_full | Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants |
| title_fullStr | Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants |
| title_full_unstemmed | Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants |
| title_short | Assesment of Heart Rate Variability As A Measure of Cardiac Autonomic Status in Psychiatric Patients Exposed to Chemical Irritants |
| title_sort | assesment of heart rate variability as a measure of cardiac autonomic status in psychiatric patients exposed to chemical irritants |
| topic | chemicals depression dsmv iv phobia |
| url | https://jcdr.net/articles/PDF/6022/12896_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
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