Therapeutic Delivery of Soluble Fractalkine Ameliorates Vascular Dysfunction in the Diabetic Retina

Therapeutic Delivery of Soluble Fractalkine Ameliorates Vascular Dysfunction in the Diabetic Retina

Diabetic retinopathy (DR)-associated vision loss is a devastating disease affecting the working-age population. Retinal pathology is due to leakage of serum components into retinal tissues, activation of resident phagocytes (microglia), and vascular and neuronal damage. While short-term intervention...

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Bibliographic Details
Main Authors: Derek Rodriguez, Kaira A. Church, Chelsea T. Smith, Difernando Vanegas, Sandra M. Cardona, Isabel A. Muzzio, Kevin R. Nash, Astrid E. Cardona
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
microglia
macrophages
fractalkine
vasculature
diabetic retinopathy
gene therapy
Online Access:https://www.mdpi.com/1422-0067/25/3/1727

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