New oral anticoagulants: key messages for clinicians

New oral anticoagulants are an effective and safe alternative to vitamin K antagonists in many fields of clinical practice. The use of the direct inhibitors of activated Factor II (dabigatran) and activated Factor X (apixaban and rivaroxaban), both in patients with non-valvular atrial fibrillation (...

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Main Authors: Matteo Giorgi-Pierfranceschi, Chiara Cattabiani, Francesco Dentali
Format: Article
Language:English
Published: PAGEPress Publications 2013-12-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/465
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author Matteo Giorgi-Pierfranceschi
Chiara Cattabiani
Francesco Dentali
author_facet Matteo Giorgi-Pierfranceschi
Chiara Cattabiani
Francesco Dentali
author_sort Matteo Giorgi-Pierfranceschi
collection DOAJ
description New oral anticoagulants are an effective and safe alternative to vitamin K antagonists in many fields of clinical practice. The use of the direct inhibitors of activated Factor II (dabigatran) and activated Factor X (apixaban and rivaroxaban), both in patients with non-valvular atrial fibrillation (NVAF) and those with acute venous thromboembolism (VTE), is of great interest for internal medicine physicians. This paper aims to give practical guidance on management (starting therapy, follow up and bleeding complications) of patients treated with dabigatran, rivaroxaban or apixaban for NVAF or acute VTE providing practical tables concerning the phases of therapy, management of complications, drug interaction and dose adjustment if renal impairment occurs.
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spelling doaj.art-06f0b7cba8bd4aefa42a22c25fd585ef2023-12-02T19:03:27ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522013-12-0178S748410.4081/itjm.2013.s8.74392New oral anticoagulants: key messages for cliniciansMatteo Giorgi-Pierfranceschi0Chiara Cattabiani1Francesco Dentali2Emergency Department, Hospital of val d'Arda, PiacenzaEmergency Department, Hospital of val d'Arda, PiacenzaInternal Medicine Department, University of Insubria, VareseNew oral anticoagulants are an effective and safe alternative to vitamin K antagonists in many fields of clinical practice. The use of the direct inhibitors of activated Factor II (dabigatran) and activated Factor X (apixaban and rivaroxaban), both in patients with non-valvular atrial fibrillation (NVAF) and those with acute venous thromboembolism (VTE), is of great interest for internal medicine physicians. This paper aims to give practical guidance on management (starting therapy, follow up and bleeding complications) of patients treated with dabigatran, rivaroxaban or apixaban for NVAF or acute VTE providing practical tables concerning the phases of therapy, management of complications, drug interaction and dose adjustment if renal impairment occurs.http://www.italjmed.org/index.php/ijm/article/view/465new oral anticoagulants, internal medicine, management checklist.
spellingShingle Matteo Giorgi-Pierfranceschi
Chiara Cattabiani
Francesco Dentali
New oral anticoagulants: key messages for clinicians
Italian Journal of Medicine
new oral anticoagulants, internal medicine, management checklist.
title New oral anticoagulants: key messages for clinicians
title_full New oral anticoagulants: key messages for clinicians
title_fullStr New oral anticoagulants: key messages for clinicians
title_full_unstemmed New oral anticoagulants: key messages for clinicians
title_short New oral anticoagulants: key messages for clinicians
title_sort new oral anticoagulants key messages for clinicians
topic new oral anticoagulants, internal medicine, management checklist.
url http://www.italjmed.org/index.php/ijm/article/view/465
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