Experimental analysis and thermodynamic modelling of lenalidomide solubility in supercritical carbon dioxide

Experimental analysis and thermodynamic modelling of lenalidomide solubility in supercritical carbon dioxide

Reduction of the size of pharmaceutical particles to micro/nano scale is an approved strategy to enhance their dissolution rate at decremented side effects. Production of drug micro/nanoparticles via a supercritical carbon dioxide (sc-CO2)- based process requires accurate data on the drug solubility...

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Bibliographic Details
Main Authors:	Seyed Ali Sajadian, Mitra Amani, Nedasadat Saadati Ardestani, Saeed Shirazian
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	Arabian Journal of Chemistry
Subjects:	Lenalidomide Solubility Supercritical carbon dioxide Empirical model Modified Wilson’s model Soave-Redlich-Kwong (SRK) equation of state
Online Access:	http://www.sciencedirect.com/science/article/pii/S187853522200137X

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