Selective optogenetic modulation of the PBN terminals in the lateral hypothalamic area and basal forebrain regulates emergence from isoflurane anesthesia in mice
Abstract While the mechanism of general anesthesia has been extensively studied, the underlying neural circuitry has yet to be fully understood. The parabrachial nucleus (PBN) plays a crucial role in modulating wakefulness and promoting arousal from general anesthesia. However, the specific role of...
Main Authors: | Kai Lu, Zhenhuan Wang, Ning Bai, Ziyu Zhao, Xinrong Zhao, Yun He |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
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Series: | BMC Anesthesiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12871-023-02294-8 |
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