A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants

A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants

Abstract The current COVID-19 pandemic has heavily burdened the global public health system and may keep simmering for years. The frequent emergence of immune escape variants have spurred the search for prophylactic vaccines and therapeutic antibodies that confer broad protection against SARS-CoV-2...

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Bibliographic Details
Main Authors: Zhenlin Yang, Yulu Wang, Yujia Jin, Yuanfei Zhu, Yanling Wu, Cheng Li, Yu Kong, Wenping Song, Xiaolong Tian, Wuqiang Zhan, Ailing Huang, Shanshan Zhou, Shuai Xia, Xiaoxu Tian, Chao Peng, Cuicui Chen, Yibing Shi, Gaowei Hu, Shujuan Du, Yuyan Wang, Youhua Xie, Shibo Jiang, Lu Lu, Lei Sun, Yuanlin Song, Tianlei Ying
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00810-1

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