A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

Abstract The road from transcription to protein synthesis is paved with many obstacles, allowing for several modes of post-transcriptional regulation of gene expression. A fundamental player in mRNA biology is DDX3X, an RNA binding protein that canonically regulates mRNA translation. By monitoring d...

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Bibliographic Details
Main Authors: Ziad Jowhar, Albert Xu, Srivats Venkataramanan, Francesco Dossena, Mariah L Hoye, Debra L Silver, Stephen N Floor, Lorenzo Calviello
Format: Article
Language:English
Published: Springer Nature 2024-01-01
Series:Molecular Systems Biology
Subjects:
Transcriptomics
DDX3X
mRNA Biology
Translation
Computational Biology
Online Access:https://doi.org/10.1038/s44320-024-00013-0

Internet

https://doi.org/10.1038/s44320-024-00013-0

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