Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon
Background: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanali...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Interdisciplinary Neurosurgery |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751920301213 |
| _version_ | 1819057539966304256 |
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| author | Blanca Serrano Serrano Francisco Hernández Fernández Nicolás López Hernández Elena Elvira Soler Giorgio Barbieri Juan D. Molina Nuevo |
| author_facet | Blanca Serrano Serrano Francisco Hernández Fernández Nicolás López Hernández Elena Elvira Soler Giorgio Barbieri Juan D. Molina Nuevo |
| author_sort | Blanca Serrano Serrano |
| collection | DOAJ |
| description | Background: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanalization. In this context, the ELUTAX “3″ drug-eluting balloon has been designed for neurological procedures. Nevertheless, there is not enough clinical evidence of this balloon. We report our experience with ELUTAX “3” during mechanical thrombectomy, explaining the technical details and the outcome of the procedure, the subsequent management and the clinical evolution of the patients. Methods: We report four cases of patients with acute stroke due to intracranial atherosclerosis who were treated with the Elutax “3″ drug-eluting-balloon. Results: Using the Elutax “3″ we achieved a complete recovery of the occluded arteries caliber (mTICI 3) and a good performance status of our patients on discharge, with the only remarkable complication of a mild asymptomatic subarachnoid bleeding in one of them. The 90-days mRS in those patients was less or equal than 2, and they have not experienced recurrence of the strokes in the long term follow-up. Conclusions: In our experience, the Elutax “3″ might be a safe and effective therapeutic option in acute large vessel occlusion secondary to intracranial atherosclerotic disease. However, further studies will be necessary to evaluate the efficacy and safety of this device. |
| first_indexed | 2024-12-21T13:40:55Z |
| format | Article |
| id | doaj.art-06f6cbb9e9ed4ff0aaecd70d2914a203 |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-12-21T13:40:55Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-06f6cbb9e9ed4ff0aaecd70d2914a2032022-12-21T19:02:00ZengElsevierInterdisciplinary Neurosurgery2214-75192020-12-0122100768Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloonBlanca Serrano Serrano0Francisco Hernández Fernández1Nicolás López Hernández2Elena Elvira Soler3Giorgio Barbieri4Juan D. Molina Nuevo5Neurology Department, Hospital General Universitario de Alicante, Spain; Corresponding author at: C/ Bailarin José Espadero, 12, escalera 5, 1C, 03015 Alicante, Spain.Neurology Department, Complejo Hospitalario Universitario de Albacete, SpainNeurology Department, Hospital General Universitario de Alicante, SpainNeurology Department, Hospital General Universitario de Alicante, SpainRadiology Department, Hospital General Universitario de Alicante, SpainRadiology Department, Complejo Hospitalario Universitario de Albacete, SpainBackground: Intracranial atherosclerotic disease is an important cause of ischemic stroke due to large vessel occlusion. The acute management of these occlusions is challenging and associates an important risk of complications, especially when mechanical thrombectomy does not achieve vessel recanalization. In this context, the ELUTAX “3″ drug-eluting balloon has been designed for neurological procedures. Nevertheless, there is not enough clinical evidence of this balloon. We report our experience with ELUTAX “3” during mechanical thrombectomy, explaining the technical details and the outcome of the procedure, the subsequent management and the clinical evolution of the patients. Methods: We report four cases of patients with acute stroke due to intracranial atherosclerosis who were treated with the Elutax “3″ drug-eluting-balloon. Results: Using the Elutax “3″ we achieved a complete recovery of the occluded arteries caliber (mTICI 3) and a good performance status of our patients on discharge, with the only remarkable complication of a mild asymptomatic subarachnoid bleeding in one of them. The 90-days mRS in those patients was less or equal than 2, and they have not experienced recurrence of the strokes in the long term follow-up. Conclusions: In our experience, the Elutax “3″ might be a safe and effective therapeutic option in acute large vessel occlusion secondary to intracranial atherosclerotic disease. However, further studies will be necessary to evaluate the efficacy and safety of this device.http://www.sciencedirect.com/science/article/pii/S2214751920301213 |
| spellingShingle | Blanca Serrano Serrano Francisco Hernández Fernández Nicolás López Hernández Elena Elvira Soler Giorgio Barbieri Juan D. Molina Nuevo Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon Interdisciplinary Neurosurgery |
| title | Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon |
| title_full | Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon |
| title_fullStr | Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon |
| title_full_unstemmed | Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon |
| title_short | Treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with ELUTAX “3″ drug-eluting balloon |
| title_sort | treatment of acute occlusion due to intracranial atherosclerosis by angioplasty with elutax 3 drug eluting balloon |
| url | http://www.sciencedirect.com/science/article/pii/S2214751920301213 |
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