Interpretation According to Clone-Specific PD-L1 Cutoffs Reveals Better Concordance in Muscle-Invasive Urothelial Carcinoma

Interpretation According to Clone-Specific PD-L1 Cutoffs Reveals Better Concordance in Muscle-Invasive Urothelial Carcinoma

Because immune checkpoint inhibitors have been approved for treating advanced urothelial carcinoma (UC), programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) assays have been widely used as companion or complementary diagnostic tests for predicting treatment outcomes. Because different clone...

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Bibliographic Details
Main Authors: Tzu-Hao Huang, Wei Cheng, Yeh-Han Wang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Diagnostics
Subjects:
PD-L1
scoring algorithm
harmonization
urothelial carcinoma
concordance
molecular phenotype
Online Access:https://www.mdpi.com/2075-4418/11/3/448

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