Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

ABSTRACT Classified as a biosafety level 4 (BSL4) select agent, Nipah virus (NiV) is a deadly henipavirus in the Paramyxoviridae family, with a nearly 75% mortality rate in humans, underscoring its global and animal health importance. Elucidating the process of viral particle production in host cell...

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Bibliographic Details
Main Authors: Gunner P. Johnston, Birgit Bradel-Tretheway, Paul D. Piehowski, Heather M. Brewer, Bom Nae Rin Lee, Nicholas T. Usher, J. Lizbeth Reyes Zamora, Victoria Ortega, Erik M. Contreras, Jeremy R. Teuton, Jason P. Wendler, Keesha M. Matz, Joshua N. Adkins, Hector C. Aguilar
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mSystems
Subjects:
Nipah virus
paramyxovirus
proteomics
vesicular trafficking
endocytosis
cytoskeleton
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00194-19

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