Reno-endocrinal disorders: A basic understanding of the molecular genetics
The successful management of endocrine diseases is greatly helped by the complete understanding of the underlying pathology. The knowledge about the molecular genetics contributes immensely in the appropriate identification of the causative factors of the diseases and their subsequent management. Th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=158;epage=163;aulast=Bajwa |
| _version_ | 1818533436140290048 |
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| author | Sukhminder Jit Singh Bajwa Ishwardip Singh Kwatra |
| author_facet | Sukhminder Jit Singh Bajwa Ishwardip Singh Kwatra |
| author_sort | Sukhminder Jit Singh Bajwa |
| collection | DOAJ |
| description | The successful management of endocrine diseases is greatly helped by the complete understanding of the underlying pathology. The knowledge about the molecular genetics contributes immensely in the appropriate identification of the causative factors of the diseases and their subsequent management. The fields of nephrology and endocrinology are also interrelated to a large extent. Besides performing the secretory functions, the renal tissue also acts as target organ for many hormones such as antidiuretic hormone (ADH), atrial natriuretic peptides (ANP), and aldosterone. Understanding the molecular genetics of these hormones is important because the therapeutic interventions in many of these conditions is related to shared renal and endocrine functions, including the anemia of renal disease, chronic kidney disease, mineral bone disorders, and hypertension related to chronic kidney disease. Their understanding and in-depth knowledge is very essential in designing and formulating the therapeutic plans and innovating new management strategies. However, we still have to go a long way in order to completely understand the various confounding causative relationships between the pathology and disease of these reno-endocrinal manifestations. |
| first_indexed | 2024-12-11T17:58:40Z |
| format | Article |
| id | doaj.art-06fd9f13fd394460a82bbea856a61193 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-12-11T17:58:40Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-06fd9f13fd394460a82bbea856a611932022-12-22T00:55:59ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116215816310.4103/2230-8210.93731Reno-endocrinal disorders: A basic understanding of the molecular geneticsSukhminder Jit Singh BajwaIshwardip Singh KwatraThe successful management of endocrine diseases is greatly helped by the complete understanding of the underlying pathology. The knowledge about the molecular genetics contributes immensely in the appropriate identification of the causative factors of the diseases and their subsequent management. The fields of nephrology and endocrinology are also interrelated to a large extent. Besides performing the secretory functions, the renal tissue also acts as target organ for many hormones such as antidiuretic hormone (ADH), atrial natriuretic peptides (ANP), and aldosterone. Understanding the molecular genetics of these hormones is important because the therapeutic interventions in many of these conditions is related to shared renal and endocrine functions, including the anemia of renal disease, chronic kidney disease, mineral bone disorders, and hypertension related to chronic kidney disease. Their understanding and in-depth knowledge is very essential in designing and formulating the therapeutic plans and innovating new management strategies. However, we still have to go a long way in order to completely understand the various confounding causative relationships between the pathology and disease of these reno-endocrinal manifestations.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=158;epage=163;aulast=BajwaErythropoietinmolecular geneticsparathyroid hormonereninvitamin D |
| spellingShingle | Sukhminder Jit Singh Bajwa Ishwardip Singh Kwatra Reno-endocrinal disorders: A basic understanding of the molecular genetics Indian Journal of Endocrinology and Metabolism Erythropoietin molecular genetics parathyroid hormone renin vitamin D |
| title | Reno-endocrinal disorders: A basic understanding of the molecular genetics |
| title_full | Reno-endocrinal disorders: A basic understanding of the molecular genetics |
| title_fullStr | Reno-endocrinal disorders: A basic understanding of the molecular genetics |
| title_full_unstemmed | Reno-endocrinal disorders: A basic understanding of the molecular genetics |
| title_short | Reno-endocrinal disorders: A basic understanding of the molecular genetics |
| title_sort | reno endocrinal disorders a basic understanding of the molecular genetics |
| topic | Erythropoietin molecular genetics parathyroid hormone renin vitamin D |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=158;epage=163;aulast=Bajwa |
| work_keys_str_mv | AT sukhminderjitsinghbajwa renoendocrinaldisordersabasicunderstandingofthemoleculargenetics AT ishwardipsinghkwatra renoendocrinaldisordersabasicunderstandingofthemoleculargenetics |