Establishment and Comprehensive Molecular Characterization of an Immortalized Glioblastoma Cell Line from a Brazilian Patient
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, with few effective treatment strategies. The research on the development of new treatments is often constrained by the limitations of preclinical models, which fail to accurately replicate the disease’s essential cha...
Main Authors: | Fernanda F. da Silva, Fernanda C. S. Lupinacci, Bruno D. S. Elias, Adriano O. Beserra, Paulo Sanematsu, Martin Roffe, Leslie D. Kulikowski, Felipe D’almeida Costa, Tiago G. Santos, Glaucia N. M. Hajj |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/21/15861 |
Similar Items
-
Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models
by: Andrea Mancini, et al.
Published: (2022-11-01) -
Unveiling Novel Avenues in mTOR-Targeted Therapeutics: Advancements in Glioblastoma Treatment
by: Shilpi Singh, et al.
Published: (2023-10-01) -
Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma
by: Amir Barzegar Behrooz, et al.
Published: (2022-01-01) -
The Bumpy Road towards mTOR Inhibition in Glioblastoma: Quo Vadis?
by: Kostas A. Papavassiliou, et al.
Published: (2021-12-01) -
Therapeutic Potential of Autophagy in Glioblastoma Treatment With Phosphoinositide 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway Inhibitors
by: Qin Xia, et al.
Published: (2020-10-01)