Phthalates: toxicology and food safety - a review

Phthalates are organic substances used mainly as plasticisers in the manufacture of plastics. They are ubiquitous in the environment. Although tests in rodents have demonstrated numerous negative effects of phthalates, it is still unclear whether the exposure to phthalates may also damage human heal...

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Main Authors: Přemysl Mikula, Zdeňka Svobodová, Miriam Smutná
Format: Article
Language:English
Published: Czech Academy of Agricultural Sciences 2005-12-01
Series:Czech Journal of Food Sciences
Subjects:
Online Access:https://cjfs.agriculturejournals.cz/artkey/cjf-200506-0001_phthalates-toxicology-and-food-safety-a-review.php
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author Přemysl Mikula
Zdeňka Svobodová
Miriam Smutná
author_facet Přemysl Mikula
Zdeňka Svobodová
Miriam Smutná
author_sort Přemysl Mikula
collection DOAJ
description Phthalates are organic substances used mainly as plasticisers in the manufacture of plastics. They are ubiquitous in the environment. Although tests in rodents have demonstrated numerous negative effects of phthalates, it is still unclear whether the exposure to phthalates may also damage human health. This paper describes phthalate toxicity and toxicokinetics, explains the mechanisms of phthalate action, and outlines the issues relating to the presence of phthalates in foods.
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spelling doaj.art-07031e3e346f401798d36751b22e9d1e2023-02-23T03:26:58ZengCzech Academy of Agricultural SciencesCzech Journal of Food Sciences1212-18001805-93172005-12-0123621722310.17221/3394-CJFScjf-200506-0001Phthalates: toxicology and food safety - a reviewPřemysl Mikula0Zdeňka Svobodová1Miriam Smutná2Department of Veterinary Public Health and Toxicology andDepartment of Veterinary Public Health and Toxicology andDepartment of Biochemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences, Brno, Czech RepublicPhthalates are organic substances used mainly as plasticisers in the manufacture of plastics. They are ubiquitous in the environment. Although tests in rodents have demonstrated numerous negative effects of phthalates, it is still unclear whether the exposure to phthalates may also damage human health. This paper describes phthalate toxicity and toxicokinetics, explains the mechanisms of phthalate action, and outlines the issues relating to the presence of phthalates in foods.https://cjfs.agriculturejournals.cz/artkey/cjf-200506-0001_phthalates-toxicology-and-food-safety-a-review.phpdi(2-ethylhexyl)phthalatedibutyl phthalateperoxisome proliferatorsreproductive toxicity
spellingShingle Přemysl Mikula
Zdeňka Svobodová
Miriam Smutná
Phthalates: toxicology and food safety - a review
Czech Journal of Food Sciences
di(2-ethylhexyl)phthalate
dibutyl phthalate
peroxisome proliferators
reproductive toxicity
title Phthalates: toxicology and food safety - a review
title_full Phthalates: toxicology and food safety - a review
title_fullStr Phthalates: toxicology and food safety - a review
title_full_unstemmed Phthalates: toxicology and food safety - a review
title_short Phthalates: toxicology and food safety - a review
title_sort phthalates toxicology and food safety a review
topic di(2-ethylhexyl)phthalate
dibutyl phthalate
peroxisome proliferators
reproductive toxicity
url https://cjfs.agriculturejournals.cz/artkey/cjf-200506-0001_phthalates-toxicology-and-food-safety-a-review.php
work_keys_str_mv AT premyslmikula phthalatestoxicologyandfoodsafetyareview
AT zdenkasvobodova phthalatestoxicologyandfoodsafetyareview
AT miriamsmutna phthalatestoxicologyandfoodsafetyareview