Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction
In the early days of assisted reproductive technology (ART), the main target was achieving gestation. Success rates were low, and multiple embryo transfers became common practice, with multiple pregnancies being 20 times higher than in natural conception. Multiple pregnancy is associated with a high...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2021-04-01
|
| Series: | Advances in Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/almed-2021-0013 |
| _version_ | 1827916260513415168 |
|---|---|
| author | Reimundo Pilar Gutiérrez Romero Javier M. Rodríguez Pérez Tamara Veiga Ernesto |
| author_facet | Reimundo Pilar Gutiérrez Romero Javier M. Rodríguez Pérez Tamara Veiga Ernesto |
| author_sort | Reimundo Pilar |
| collection | DOAJ |
| description | In the early days of assisted reproductive technology (ART), the main target was achieving gestation. Success rates were low, and multiple embryo transfers became common practice, with multiple pregnancies being 20 times higher than in natural conception. Multiple pregnancy is associated with a higher risk of complications for the mother and the baby than a singleton pregnancy. Added to healthcare costs, multiple pregnancy also involves other costs and psychosocial risks, with a high social and health costs. At present, success rates of assisted human reproduction (AHR) have improved dramatically, partially due to advances in laboratory techniques such as culture of blastocyst-stage embryos and vitrification. Additionally, there is a wide range of counseling, health and economic policies that have demonstrated being effective in increasing single-embryo transfer (SET) practices and reducing multiple pregnancies, which ensures satisfactory success rates. Therefore, single-embryo transfer emerges as the approach of choice for AHR to result in a full-term healthy newborn. |
| first_indexed | 2024-03-13T03:12:33Z |
| format | Article |
| id | doaj.art-0707d922f088488a8a1040b669be4457 |
| institution | Directory Open Access Journal |
| issn | 2628-491X |
| language | English |
| last_indexed | 2024-03-13T03:12:33Z |
| publishDate | 2021-04-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Advances in Laboratory Medicine |
| spelling | doaj.art-0707d922f088488a8a1040b669be44572023-06-26T10:46:03ZengDe GruyterAdvances in Laboratory Medicine2628-491X2021-04-012217918810.1515/almed-2021-0013Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproductionReimundo Pilar0Gutiérrez Romero Javier M.1Rodríguez Pérez Tamara2Veiga Ernesto3Laboratory of Assisted Reproduction and Andrology, Area of Clinical Biochemistry, Vall d’Hebron Clinical Laboratories, Vall d’Hebron University Hospital, Barcelona, SpainClinical Management Unit of Clinical Laboratories, Puerta del Mar University Hospital, Cadiz, SpainLaboratory of Andrology and Assisted Reproduction Techniques, Service of Clinical Biochemistry, La Paz University Hospital, Madrid, SpainUnit of Assisted Human Reproduction, Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), SERGAS, Santiago de Compostela, SpainIn the early days of assisted reproductive technology (ART), the main target was achieving gestation. Success rates were low, and multiple embryo transfers became common practice, with multiple pregnancies being 20 times higher than in natural conception. Multiple pregnancy is associated with a higher risk of complications for the mother and the baby than a singleton pregnancy. Added to healthcare costs, multiple pregnancy also involves other costs and psychosocial risks, with a high social and health costs. At present, success rates of assisted human reproduction (AHR) have improved dramatically, partially due to advances in laboratory techniques such as culture of blastocyst-stage embryos and vitrification. Additionally, there is a wide range of counseling, health and economic policies that have demonstrated being effective in increasing single-embryo transfer (SET) practices and reducing multiple pregnancies, which ensures satisfactory success rates. Therefore, single-embryo transfer emerges as the approach of choice for AHR to result in a full-term healthy newborn.https://doi.org/10.1515/almed-2021-0013assisted reproduction techniqueselective single-embryo transferinfertilityin vitro fertilizationmultiple deliverymultiple pregnancy |
| spellingShingle | Reimundo Pilar Gutiérrez Romero Javier M. Rodríguez Pérez Tamara Veiga Ernesto Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction Advances in Laboratory Medicine assisted reproduction techniques elective single-embryo transfer infertility in vitro fertilization multiple delivery multiple pregnancy |
| title | Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| title_full | Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| title_fullStr | Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| title_full_unstemmed | Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| title_short | Single-embryo transfer: a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| title_sort | single embryo transfer a key strategy to reduce the risk for multiple pregnancy in assisted human reproduction |
| topic | assisted reproduction techniques elective single-embryo transfer infertility in vitro fertilization multiple delivery multiple pregnancy |
| url | https://doi.org/10.1515/almed-2021-0013 |
| work_keys_str_mv | AT reimundopilar singleembryotransferakeystrategytoreducetheriskformultiplepregnancyinassistedhumanreproduction AT gutierrezromerojavierm singleembryotransferakeystrategytoreducetheriskformultiplepregnancyinassistedhumanreproduction AT rodriguezpereztamara singleembryotransferakeystrategytoreducetheriskformultiplepregnancyinassistedhumanreproduction AT veigaernesto singleembryotransferakeystrategytoreducetheriskformultiplepregnancyinassistedhumanreproduction |