Infant antibody and B-cell responses following confirmed pediatric GII.17 norovirus infections functionally distinguish GII.17 genetic clusters

Infant antibody and B-cell responses following confirmed pediatric GII.17 norovirus infections functionally distinguish GII.17 genetic clusters

Genogroup II (GII) noroviruses are a major cause of diarrheal disease burden in children in both high- and low-income countries. GII.17 noroviruses are composed of distinct genetic clusters (I, II, IIIa, and IIIb) and have shown potential for replacing historically more prevalent GII.4 strains, but...

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Bibliographic Details
Main Authors: Camilla A. Strother, Paul D. Brewer-Jensen, Sylvia Becker-Dreps, Omar Zepeda, Samantha May, Fredman Gonzalez, Yaoska Reyes, Benjamin D. McElvany, April M. Averill, Michael L. Mallory, Anna M. Montmayeur, Verónica P. Costantini, Jan Vinjé, Ralph S. Baric, Filemon Bucardo, Lisa C. Lindesmith, Sean A. Diehl
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
norovirus
children
GII.17
blockade antibody
variants of concern
memory B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1229724/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1229724/full

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