Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era
Like other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate. A growing number of studies have shown that oleanolic acid exhibits a variety of beneficial properties, including antiviral, anti-in...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
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| Series: | Agriculture |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0472/12/12/2142 |
| _version_ | 1827642232350441472 |
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| author | Kun Wang Qinyue Lu Xiang Cao Yuhao Wang Yanni Wu Zhi Chen Zhangping Yang |
| author_facet | Kun Wang Qinyue Lu Xiang Cao Yuhao Wang Yanni Wu Zhi Chen Zhangping Yang |
| author_sort | Kun Wang |
| collection | DOAJ |
| description | Like other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate. A growing number of studies have shown that oleanolic acid exhibits a variety of beneficial properties, including antiviral, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. Additionally, the rapid advance of nanotechnology has dramatically improved oleanolic acid’s bioavailability and minimized its disadvantages, leading to unexpected changes in its pharmacological activity and use. Therefore, our aim was to review the progress of research on the distribution and biological properties of oleanolic acid in plants and to discuss new pharmaceutical approaches for oleanolic acid. |
| first_indexed | 2024-03-09T17:25:37Z |
| format | Article |
| id | doaj.art-07101d2b7ed444f092ca5606ab7be5c2 |
| institution | Directory Open Access Journal |
| issn | 2077-0472 |
| language | English |
| last_indexed | 2024-03-09T17:25:37Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Agriculture |
| spelling | doaj.art-07101d2b7ed444f092ca5606ab7be5c22023-11-24T12:42:07ZengMDPI AGAgriculture2077-04722022-12-011212214210.3390/agriculture12122142Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano EraKun Wang0Qinyue Lu1Xiang Cao2Yuhao Wang3Yanni Wu4Zhi Chen5Zhangping Yang6College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaLike other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate. A growing number of studies have shown that oleanolic acid exhibits a variety of beneficial properties, including antiviral, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. Additionally, the rapid advance of nanotechnology has dramatically improved oleanolic acid’s bioavailability and minimized its disadvantages, leading to unexpected changes in its pharmacological activity and use. Therefore, our aim was to review the progress of research on the distribution and biological properties of oleanolic acid in plants and to discuss new pharmaceutical approaches for oleanolic acid.https://www.mdpi.com/2077-0472/12/12/2142oleanolic acidnanonanoparticlesanti-inflammatoryantitumor |
| spellingShingle | Kun Wang Qinyue Lu Xiang Cao Yuhao Wang Yanni Wu Zhi Chen Zhangping Yang Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era Agriculture oleanolic acid nano nanoparticles anti-inflammatory antitumor |
| title | Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era |
| title_full | Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era |
| title_fullStr | Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era |
| title_full_unstemmed | Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era |
| title_short | Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era |
| title_sort | application and development of natural plant metabolite oleanolic acid in the nano era |
| topic | oleanolic acid nano nanoparticles anti-inflammatory antitumor |
| url | https://www.mdpi.com/2077-0472/12/12/2142 |
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