Effects of Psychostimulant Drugs on Developing Brain
Although psychostimulants have been used for the treatment of attention deficit hyperactivity disorder for approximately 70 years, little is known about the long term effects of these drugs on developing brain. The observable effects of psychostimulants are influenced by the timing of exposure, the...
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Format: | Article |
Language: | English |
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Psikiyatride Güncel Yaklaşımlar
2013-08-01
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Series: | Psikiyatride Güncel Yaklaşımlar |
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Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=32051 |
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author | Ibrahim Durukan Murat Erdem Koray Kara Dursun Karaman |
author_facet | Ibrahim Durukan Murat Erdem Koray Kara Dursun Karaman |
author_sort | Ibrahim Durukan |
collection | DOAJ |
description | Although psychostimulants have been used for the treatment of attention deficit hyperactivity disorder for approximately 70 years, little is known about the long term effects of these drugs on developing brain. The observable effects of psychostimulants are influenced by the timing of exposure, the age of examination after drug exposure and sex. Preclinical studies point out that chronic psychostimulant exposure before adolescence cause reverse sensitization or tolerance and this leads to reduction in stimulant effectiveness in adolesecence and adulthood. Preclinical studies show the potential long term effects of psychostimulants. But it is necessary to investigate the relationship between preclinical effects and clinical practice. A developmental approach is needed to understand the impact of pediatric medications on the brain that includes assessment at multiple ages to completely characterize the long term effects of these medications. The aim of this paper is to review the effects of psychostimulants on developing brain. |
first_indexed | 2024-03-08T07:02:22Z |
format | Article |
id | doaj.art-071403497fad425c81de5551a73f864b |
institution | Directory Open Access Journal |
issn | 1309-0658 |
language | English |
last_indexed | 2024-03-08T07:02:22Z |
publishDate | 2013-08-01 |
publisher | Psikiyatride Güncel Yaklaşımlar |
record_format | Article |
series | Psikiyatride Güncel Yaklaşımlar |
spelling | doaj.art-071403497fad425c81de5551a73f864b2024-02-03T05:25:54ZengPsikiyatride Güncel YaklaşımlarPsikiyatride Güncel Yaklaşımlar1309-06582013-08-015452853910.5455/cap.2013053232051Effects of Psychostimulant Drugs on Developing BrainIbrahim Durukan0Murat Erdem1Koray Kara2Dursun Karaman3GATA Cocuk ve Ergen Ruh Sagligi ve Hst. AD: GATA Ruh Sagligi ve Hst. AD GATA Cocuk ve Ergen Ruh Sagligi ve Hst. AD: GATA Cocuk ve Ergen Ruh Sagligi ve Hst. AD:Although psychostimulants have been used for the treatment of attention deficit hyperactivity disorder for approximately 70 years, little is known about the long term effects of these drugs on developing brain. The observable effects of psychostimulants are influenced by the timing of exposure, the age of examination after drug exposure and sex. Preclinical studies point out that chronic psychostimulant exposure before adolescence cause reverse sensitization or tolerance and this leads to reduction in stimulant effectiveness in adolesecence and adulthood. Preclinical studies show the potential long term effects of psychostimulants. But it is necessary to investigate the relationship between preclinical effects and clinical practice. A developmental approach is needed to understand the impact of pediatric medications on the brain that includes assessment at multiple ages to completely characterize the long term effects of these medications. The aim of this paper is to review the effects of psychostimulants on developing brain.http://www.scopemed.org/fulltextpdf.php?mno=32051Psychostimulantdeveloping brainattention deficit hyperactivity disorder |
spellingShingle | Ibrahim Durukan Murat Erdem Koray Kara Dursun Karaman Effects of Psychostimulant Drugs on Developing Brain Psikiyatride Güncel Yaklaşımlar Psychostimulant developing brain attention deficit hyperactivity disorder |
title | Effects of Psychostimulant Drugs on Developing Brain |
title_full | Effects of Psychostimulant Drugs on Developing Brain |
title_fullStr | Effects of Psychostimulant Drugs on Developing Brain |
title_full_unstemmed | Effects of Psychostimulant Drugs on Developing Brain |
title_short | Effects of Psychostimulant Drugs on Developing Brain |
title_sort | effects of psychostimulant drugs on developing brain |
topic | Psychostimulant developing brain attention deficit hyperactivity disorder |
url | http://www.scopemed.org/fulltextpdf.php?mno=32051 |
work_keys_str_mv | AT ibrahimdurukan effectsofpsychostimulantdrugsondevelopingbrain AT muraterdem effectsofpsychostimulantdrugsondevelopingbrain AT koraykara effectsofpsychostimulantdrugsondevelopingbrain AT dursunkaraman effectsofpsychostimulantdrugsondevelopingbrain |