Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger

A variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been describe...

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Main Authors: Koji Nakajima, Takahide Kaneko, Takayuki Aizu, Hajime Nakano, Yasushi Matsuzaki, Daisuke Sawamura
Format: Article
Language:English
Published: Karger Publishers 2013-08-01
Series:Case Reports in Dermatology
Subjects:
Online Access:http://www.karger.com/Article/FullText/354536
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author Koji Nakajima
Takahide Kaneko
Takayuki Aizu
Hajime Nakano
Yasushi Matsuzaki
Daisuke Sawamura
author_facet Koji Nakajima
Takahide Kaneko
Takayuki Aizu
Hajime Nakano
Yasushi Matsuzaki
Daisuke Sawamura
author_sort Koji Nakajima
collection DOAJ
description A variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been described in detail, and one dermatopathologic report focused on the presence of signet-ring cells briefly described in clinical data of 6 cases. Interestingly, in these reports, the skin lesions of 10 cases occurred exclusively in the head and neck area. This case involved a skin lesion on the back of the finger and is thus the first reported case of signet-cell cutaneous SCC that did not arise in the head and neck area. The location of this lesion, together with the histological findings compatible with actinic keratosis, support the hypothesis that the development of signet-ring SCC is related to ultraviolet light-induced damage.
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spelling doaj.art-07159a17a379430595811d186784f6db2022-12-22T02:55:45ZengKarger PublishersCase Reports in Dermatology1662-65672013-08-015221521810.1159/000354536354536Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the FingerKoji NakajimaTakahide KanekoTakayuki AizuHajime NakanoYasushi MatsuzakiDaisuke SawamuraA variety of pathologic variants of cutaneous squamous cell carcinoma (SCC) has been reported, and the signet-ring variant of cutaneous SCC is extremely uncommon. We reported an 83-year-old man with signet-ring SCC arising on the back of the finger. As far as we know, only 4 cases have been described in detail, and one dermatopathologic report focused on the presence of signet-ring cells briefly described in clinical data of 6 cases. Interestingly, in these reports, the skin lesions of 10 cases occurred exclusively in the head and neck area. This case involved a skin lesion on the back of the finger and is thus the first reported case of signet-cell cutaneous SCC that did not arise in the head and neck area. The location of this lesion, together with the histological findings compatible with actinic keratosis, support the hypothesis that the development of signet-ring SCC is related to ultraviolet light-induced damage.http://www.karger.com/Article/FullText/354536Signet-ring cellSquamous cell carcinomaSun damage
spellingShingle Koji Nakajima
Takahide Kaneko
Takayuki Aizu
Hajime Nakano
Yasushi Matsuzaki
Daisuke Sawamura
Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
Case Reports in Dermatology
Signet-ring cell
Squamous cell carcinoma
Sun damage
title Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
title_full Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
title_fullStr Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
title_full_unstemmed Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
title_short Signet-Ring Cutaneous Squamous Cell Carcinoma Arising on the Back of the Finger
title_sort signet ring cutaneous squamous cell carcinoma arising on the back of the finger
topic Signet-ring cell
Squamous cell carcinoma
Sun damage
url http://www.karger.com/Article/FullText/354536
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