Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period
Purpose: To evaluate technical outcome, diagnostic yield and safety of computed tomographic fluoroscopy-guided percutaneous core needle biopsies in patients with mediastinal masses. Methods: Overall, 155 CT fluoroscopy-guided mediastinal core needle biopsies, performed from March 2010 to June 2020 w...
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| Format: | Article |
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MDPI AG
2021-04-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/5/781 |
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| author | Caroline Burgard Robert Stahl Giovanna Negrao de Figueiredo Julien Dinkel Thomas Liebig Dania Cioni Emanuele Neri Christoph G. Trumm |
| author_facet | Caroline Burgard Robert Stahl Giovanna Negrao de Figueiredo Julien Dinkel Thomas Liebig Dania Cioni Emanuele Neri Christoph G. Trumm |
| author_sort | Caroline Burgard |
| collection | DOAJ |
| description | Purpose: To evaluate technical outcome, diagnostic yield and safety of computed tomographic fluoroscopy-guided percutaneous core needle biopsies in patients with mediastinal masses. Methods: Overall, 155 CT fluoroscopy-guided mediastinal core needle biopsies, performed from March 2010 to June 2020 were included. Size of lesion, size of needle, access path, number of success, number of biopsies per session, diagnostic yield, patient’s position, effective dose, rate of complications, tumor localization, size of tumor and histopathological diagnosis were considered. Post-interventional CT was performed, and patients observed for any complications. Complications were classified per the Society of Interventional Radiology (SIR). Results: 148 patients (age, 54.7 ± 18.2) underwent 155 CT-fluoroscopy-guided percutaneous biopsies with tumors in the anterior (114; 73.5%), middle (17; 11%) and posterior (24; 15.5%) mediastinum, of which 152 (98%) were technically successful. For placement of the biopsy needle, in 82 (52.9%) procedures a parasternal trajectory was chosen, in 36 (23.3%) a paravertebral access, in 20 (12.9%) through the lateral intercostal space and in 17 (11%) the thoracic anterior midline, respectively. A total of 136 (89.5%) of the biopsies were considered adequate for a specific histopathologic analysis. Total DLP (dose-length product) was 575.7 ± 488.8 mGy*cm. Mean lesion size was 6.0 ± 3.3 cm. Neoplastic pathology was diagnosed in 115 (75.7%) biopsies and 35 (23%) biopsy samples showed no evidence of malignancy. Minor complications were observed in 18 (11.6%) procedures and major pneumothorax requiring drainage insertion in 3 interventions (1.9%). Conclusion: CT fluoroscopy-guided percutaneous core needle biopsy of mediastinal masses is an effective and safe procedure for the initial assessment of patients with mediastinal tumors. |
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| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T11:56:36Z |
| publishDate | 2021-04-01 |
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| series | Diagnostics |
| spelling | doaj.art-071722a18ff9444b90b196c0f19c3f672023-11-21T17:14:45ZengMDPI AGDiagnostics2075-44182021-04-0111578110.3390/diagnostics11050781Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year PeriodCaroline Burgard0Robert Stahl1Giovanna Negrao de Figueiredo2Julien Dinkel3Thomas Liebig4Dania Cioni5Emanuele Neri6Christoph G. Trumm7Department of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, GermanyInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, GermanyInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, GermanyDepartment of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, ItalyDepartment of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, ItalyInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, GermanyPurpose: To evaluate technical outcome, diagnostic yield and safety of computed tomographic fluoroscopy-guided percutaneous core needle biopsies in patients with mediastinal masses. Methods: Overall, 155 CT fluoroscopy-guided mediastinal core needle biopsies, performed from March 2010 to June 2020 were included. Size of lesion, size of needle, access path, number of success, number of biopsies per session, diagnostic yield, patient’s position, effective dose, rate of complications, tumor localization, size of tumor and histopathological diagnosis were considered. Post-interventional CT was performed, and patients observed for any complications. Complications were classified per the Society of Interventional Radiology (SIR). Results: 148 patients (age, 54.7 ± 18.2) underwent 155 CT-fluoroscopy-guided percutaneous biopsies with tumors in the anterior (114; 73.5%), middle (17; 11%) and posterior (24; 15.5%) mediastinum, of which 152 (98%) were technically successful. For placement of the biopsy needle, in 82 (52.9%) procedures a parasternal trajectory was chosen, in 36 (23.3%) a paravertebral access, in 20 (12.9%) through the lateral intercostal space and in 17 (11%) the thoracic anterior midline, respectively. A total of 136 (89.5%) of the biopsies were considered adequate for a specific histopathologic analysis. Total DLP (dose-length product) was 575.7 ± 488.8 mGy*cm. Mean lesion size was 6.0 ± 3.3 cm. Neoplastic pathology was diagnosed in 115 (75.7%) biopsies and 35 (23%) biopsy samples showed no evidence of malignancy. Minor complications were observed in 18 (11.6%) procedures and major pneumothorax requiring drainage insertion in 3 interventions (1.9%). Conclusion: CT fluoroscopy-guided percutaneous core needle biopsy of mediastinal masses is an effective and safe procedure for the initial assessment of patients with mediastinal tumors.https://www.mdpi.com/2075-4418/11/5/781CT-guided biopsymediastinal massinterventional radiologycore needle biopsy |
| spellingShingle | Caroline Burgard Robert Stahl Giovanna Negrao de Figueiredo Julien Dinkel Thomas Liebig Dania Cioni Emanuele Neri Christoph G. Trumm Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period Diagnostics CT-guided biopsy mediastinal mass interventional radiology core needle biopsy |
| title | Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period |
| title_full | Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period |
| title_fullStr | Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period |
| title_full_unstemmed | Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period |
| title_short | Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period |
| title_sort | percutaneous ct fluoroscopy guided core needle biopsy of mediastinal masses technical outcome and complications of 155 procedures during a 10 year period |
| topic | CT-guided biopsy mediastinal mass interventional radiology core needle biopsy |
| url | https://www.mdpi.com/2075-4418/11/5/781 |
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