Rapid Detection of Extended-Spectrum β-Lactamases (ESBL) and AmpC β-Lactamases in Enterobacterales: Development of a Screening Panel Using the MALDI-TOF MS-Based Direct-on-Target Microdroplet Growth Assay

Rapid Detection of Extended-Spectrum β-Lactamases (ESBL) and AmpC β-Lactamases in Enterobacterales: Development of a Screening Panel Using the MALDI-TOF MS-Based Direct-on-Target Microdroplet Growth Assay

Introduction: Antibiotic resistant bacteria are a growing concern worldwide. Extended-spectrum β-lactamases (ESBL) represent the most common resistance mechanism of Gram-negative bacteria against β-lactams, underlining the need for adequate diagnostic methods that provide reliable information in the...

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Bibliographic Details
Main Authors: Carlos L. Correa-Martínez, Evgeny A. Idelevich, Katrin Sparbier, Markus Kostrzewa, Karsten Becker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
extended-spectrum beta-lactamase
AmpC beta-lactamase
MALDI-TOF mass spectrometry
rapid diagnostic assays
multiresistance
Enterobacterales
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00013/full

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