New primers for methylation-specific polymerase chain reaction enhance specificity of detecting STAT1 methylation

New primers for methylation-specific polymerase chain reaction enhance specificity of detecting STAT1 methylation

Objective: Signal transducer and activator of transcription (STAT)1 is a key tumor suppressor, which is always methylated in a variety of human cancers. However, nonspecific primers for the detection of specific promoter hypermethylation of STAT1 gene can lead to false-positive or false-negative res...

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Bibliographic Details
Main Authors:	Ming-Cheng Chang, Ying-Cheng Chiang, Chih-Ming Ho, Yu-Li Chen, Chi-An Chen, Wen-Fang Cheng, Cheng-Yang Chou
Format:	Article
Language:	English
Published:	Elsevier 2012-03-01
Series:	Taiwanese Journal of Obstetrics & Gynecology
Subjects:	methylation polymerase chain reaction signal transducer and activator of transcription 1
Online Access:	http://www.sciencedirect.com/science/article/pii/S1028455912000101

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