Chemogenetic activation of astrocytes promotes remyelination and restores cognitive deficits in visceral hypersensitive rats

Chemogenetic activation of astrocytes promotes remyelination and restores cognitive deficits in visceral hypersensitive rats

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Summary: Using a well-established chronic visceral hypersensitivity (VH) rat model, we characterized the decrease of myelin basic protein, reduced number of mature oligodendrocytes (OLs), and hypomyelination in the anterior cingulate cortex (ACC). The results of rat gambling test showed impaired dec...

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Bibliographic Details
Main Authors:	Mahadi Hasan, Zhuogui Lei, Mastura Akter, Zafar Iqbal, Faeeqa Usaila, Aruna Surendran Ramkrishnan, Ying Li
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Series:	iScience
Subjects:	Biological sciences Cognitive neuroscience Neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004222021137

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