Evaluation of all-cause mortality and cardiovascular safety in patients receiving chimeric antigen receptor T cell therapy: a prospective cohort studyResearch in context

Evaluation of all-cause mortality and cardiovascular safety in patients receiving chimeric antigen receptor T cell therapy: a prospective cohort studyResearch in context

Summary: Background: Assessment of cardiovascular risk is critical for patients with cancer. Previous retrospective studies suggest potential cardiotoxicity of CAR T cell therapies. We aimed to prospectively assess cardiotoxicity and the predictive value of cardiac biomarkers and classical risk fac...

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Bibliographic Details
Main Authors: Felix Korell, Lukas Entenmann, Sebastian Romann, Evangelos Giannitsis, Anita Schmitt, Carsten Müller-Tidow, Norbert Frey, Peter Dreger, Michael Schmitt, Lorenz H Lehmann
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:EClinicalMedicine
Subjects:
Cardiotoxicity
CAR T cells
Cardiac biomarkers
Risk stratification
Online Access:http://www.sciencedirect.com/science/article/pii/S258953702400083X

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