Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime

Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime

Lung cancer is one of the most commonly diagnosed cancer and despite therapeutic advances, mortality remains high. The long period of clinical latency associated with lung cancer provides an ideal window of opportunity to administer vaccines to at-risk individuals that can prevent tumor progression...

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Bibliographic Details
Main Authors: Zhe Zhang, Shuangshuang Lu, Louisa S. Chard Dunmall, Zhizhong Wang, Zhenguo Cheng, Zhongxian Zhang, Wenli Yan, Yongchao Chu, Dongling Gao, Na Wang, Yang Li, Jiwei Wang, Yuenan Li, Yupei Ji, Danyang Shan, Keke Li, Panpan Wang, Yunshu Dong, Jianzeng Dong, Nick R. Lemoine, Duanqing Pei, Lirong Zhang, Yaohe Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
lung cancer
vaccine
induced pluripotent stem cells
KRAS
TP53
adenovirus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01996/full

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