Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging
Robusta coffee beans contain antioxidant compounds having anti-aging properties. This study aims to determine the content of secondary metabolites in robusta coffee bean extract, anti-aging effectiveness, and the best peel-off gel mask preparation concentration. The extraction method in this study u...
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| Format: | Article |
| Language: | English |
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Universitas Ahmad Dahlan
2023-03-01
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| Series: | Pharmaciana |
| Subjects: | |
| Online Access: | http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/23965/pdf_265 |
| _version_ | 1797837948492709888 |
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| author | Angga Saputra Yasir Agesta Yesti Renita Tutik |
| author_facet | Angga Saputra Yasir Agesta Yesti Renita Tutik |
| author_sort | Angga Saputra Yasir |
| collection | DOAJ |
| description | Robusta coffee beans contain antioxidant compounds having anti-aging properties. This study aims to determine the content of secondary metabolites in robusta coffee bean extract, anti-aging effectiveness, and the best peel-off gel mask preparation concentration. The extraction method in this study used maceration with 96% ethanol as solvent. The extraction results were carried out by phytochemical screening and formulation of peel-off gel mask preparations, then tested for anti-aging effectiveness using 12 female volunteers and observed signs of aging, including pores, spots, wrinkles, and moisture for four weeks. Robusta coffee bean extraction results obtained a yield of 9.2%. The results of phytochemical screening showed that robusta coffee bean extract contains flavonoid compounds, alkaloids, tannins, and saponins. The results of the evaluation of the 0.5% formula of robusta coffee bean extract were the most preferred by volunteers. The best effectiveness and concentration test results were found in the peel-off gel mask preparation of 2% robusta coffee bean extract formula (F2) compared to blank and F1 (p-value <0.05). The percentage of improvement in the condition of the volunteers' skin, including pores, spots, wrinkles, and moisture, is 21.88 4.22%, 21.57 3.25%, 17.71 2.44%, and 21.25 3.62%, respectively. |
| first_indexed | 2024-04-09T15:34:00Z |
| format | Article |
| id | doaj.art-0733ccde366e45a681402b011bb5eabb |
| institution | Directory Open Access Journal |
| issn | 2088-4559 2477-0256 |
| language | English |
| last_indexed | 2024-04-09T15:34:00Z |
| publishDate | 2023-03-01 |
| publisher | Universitas Ahmad Dahlan |
| record_format | Article |
| series | Pharmaciana |
| spelling | doaj.art-0733ccde366e45a681402b011bb5eabb2023-04-28T03:04:45ZengUniversitas Ahmad DahlanPharmaciana2088-45592477-02562023-03-01131879910.12928/pharmaciana.v13i1.23965Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-agingAngga Saputra Yasir0Agesta Yesti Renita1Tutik2Department of Cosmetic Engineering, Sumatera Institute of TechnologyDepartment of Pharmacy, Malahayati UniversityDepartment of Pharmacy, Malahayati UniversityRobusta coffee beans contain antioxidant compounds having anti-aging properties. This study aims to determine the content of secondary metabolites in robusta coffee bean extract, anti-aging effectiveness, and the best peel-off gel mask preparation concentration. The extraction method in this study used maceration with 96% ethanol as solvent. The extraction results were carried out by phytochemical screening and formulation of peel-off gel mask preparations, then tested for anti-aging effectiveness using 12 female volunteers and observed signs of aging, including pores, spots, wrinkles, and moisture for four weeks. Robusta coffee bean extraction results obtained a yield of 9.2%. The results of phytochemical screening showed that robusta coffee bean extract contains flavonoid compounds, alkaloids, tannins, and saponins. The results of the evaluation of the 0.5% formula of robusta coffee bean extract were the most preferred by volunteers. The best effectiveness and concentration test results were found in the peel-off gel mask preparation of 2% robusta coffee bean extract formula (F2) compared to blank and F1 (p-value <0.05). The percentage of improvement in the condition of the volunteers' skin, including pores, spots, wrinkles, and moisture, is 21.88 4.22%, 21.57 3.25%, 17.71 2.44%, and 21.25 3.62%, respectively.http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/23965/pdf_265: robusta coffee bean (coffea canephora)anti-agingpeel-off gel maskskin analyzer |
| spellingShingle | Angga Saputra Yasir Agesta Yesti Renita Tutik Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging Pharmaciana : robusta coffee bean (coffea canephora) anti-aging peel-off gel mask skin analyzer |
| title | Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging |
| title_full | Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging |
| title_fullStr | Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging |
| title_full_unstemmed | Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging |
| title_short | Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging |
| title_sort | evaluation and clinical activity test of various concentrations of peel off gel mask of robusta coffee seed extract coffea canephora as anti aging |
| topic | : robusta coffee bean (coffea canephora) anti-aging peel-off gel mask skin analyzer |
| url | http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/23965/pdf_265 |
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