First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) responsible for the current pandemic has resulted in over 5 million deaths globally. More than a year has passed, still SARS-CoV-2 panic the public life. Virus isolation is of paramount importance for development of vaccines, in-vitro scre...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=133;epage=139;aulast=Jakharia |
| _version_ | 1797210073689227264 |
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| author | Aniruddha Jakharia Biswajyoti Borkakoty Sumi Pait Gautam Baruah Rahul Hazarika Dipankar Biswas |
| author_facet | Aniruddha Jakharia Biswajyoti Borkakoty Sumi Pait Gautam Baruah Rahul Hazarika Dipankar Biswas |
| author_sort | Aniruddha Jakharia |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) responsible for the current pandemic has resulted in over 5 million deaths globally. More than a year has passed, still SARS-CoV-2 panic the public life. Virus isolation is of paramount importance for development of vaccines, in-vitro screening of antiviral compounds, pathogenesis studies, etc., Many cell lines were studied for amplification and replication of SARS-CoV-2 and Vero cells were found to be ideal cell lines for isolation. In May 2020, ICMR-Regional Medical Research Centre, NE region, India, successfully established the SARS-CoV-2 culture system in Vero CCL-81 cell lines. Phylogenetic analyses of the whole genome sequences of the SARS-CoV-2 isolate (EPI_ISL_2501532 | 2020-05-19) showed monophyletic clade G and lineage B.1.1. |
| first_indexed | 2024-04-24T10:04:48Z |
| format | Article |
| id | doaj.art-07379d4e2f5f451f83ca25ec0271715f |
| institution | Directory Open Access Journal |
| issn | 0377-4929 0974-5130 |
| language | English |
| last_indexed | 2024-04-24T10:04:48Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-07379d4e2f5f451f83ca25ec0271715f2024-04-13T03:00:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-01-0167113313910.4103/ijpm.ijpm_748_21First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East IndiaAniruddha JakhariaBiswajyoti BorkakotySumi PaitGautam BaruahRahul HazarikaDipankar BiswasSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) responsible for the current pandemic has resulted in over 5 million deaths globally. More than a year has passed, still SARS-CoV-2 panic the public life. Virus isolation is of paramount importance for development of vaccines, in-vitro screening of antiviral compounds, pathogenesis studies, etc., Many cell lines were studied for amplification and replication of SARS-CoV-2 and Vero cells were found to be ideal cell lines for isolation. In May 2020, ICMR-Regional Medical Research Centre, NE region, India, successfully established the SARS-CoV-2 culture system in Vero CCL-81 cell lines. Phylogenetic analyses of the whole genome sequences of the SARS-CoV-2 isolate (EPI_ISL_2501532 | 2020-05-19) showed monophyletic clade G and lineage B.1.1.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=133;epage=139;aulast=Jakhariacovid-19sars-cov-2virus isolation |
| spellingShingle | Aniruddha Jakharia Biswajyoti Borkakoty Sumi Pait Gautam Baruah Rahul Hazarika Dipankar Biswas First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India Indian Journal of Pathology and Microbiology covid-19 sars-cov-2 virus isolation |
| title | First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India |
| title_full | First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India |
| title_fullStr | First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India |
| title_full_unstemmed | First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India |
| title_short | First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India |
| title_sort | first isolation and characterization of sars cov 2 from covid 19 patient of north east india |
| topic | covid-19 sars-cov-2 virus isolation |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=133;epage=139;aulast=Jakharia |
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