Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans.
Iron overload is known to exacerbate many infectious diseases, and conversely, iron withholding is an important defense strategy for mammalian hosts. Iron is a critical cue for Cryptococcus neoformans because the fungus senses iron to regulate elaboration of the polysaccharide capsule that is the ma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-11-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1637126?pdf=render |