Should we “eliminate” PDA shunt in preterm infants? A narrative review

The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In additio...

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Main Authors: Aimann Surak, Amneet Sidhu, Joseph Y. Ting
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2024.1257694/full
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author Aimann Surak
Amneet Sidhu
Joseph Y. Ting
author_facet Aimann Surak
Amneet Sidhu
Joseph Y. Ting
author_sort Aimann Surak
collection DOAJ
description The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach. This article provides a comprehensive review of existing literature.
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spelling doaj.art-073c6fe5e39c4382b69d81ea303cc1f32024-02-06T04:49:36ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-02-011210.3389/fped.2024.12576941257694Should we “eliminate” PDA shunt in preterm infants? A narrative reviewAimann Surak0Amneet Sidhu1Joseph Y. Ting2Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, CanadaDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, McMaster University, Hamilton, ON, CanadaDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, CanadaThe patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach. This article provides a comprehensive review of existing literature.https://www.frontiersin.org/articles/10.3389/fped.2024.1257694/fullPDApretermligationpiccoloshunt
spellingShingle Aimann Surak
Amneet Sidhu
Joseph Y. Ting
Should we “eliminate” PDA shunt in preterm infants? A narrative review
Frontiers in Pediatrics
PDA
preterm
ligation
piccolo
shunt
title Should we “eliminate” PDA shunt in preterm infants? A narrative review
title_full Should we “eliminate” PDA shunt in preterm infants? A narrative review
title_fullStr Should we “eliminate” PDA shunt in preterm infants? A narrative review
title_full_unstemmed Should we “eliminate” PDA shunt in preterm infants? A narrative review
title_short Should we “eliminate” PDA shunt in preterm infants? A narrative review
title_sort should we eliminate pda shunt in preterm infants a narrative review
topic PDA
preterm
ligation
piccolo
shunt
url https://www.frontiersin.org/articles/10.3389/fped.2024.1257694/full
work_keys_str_mv AT aimannsurak shouldweeliminatepdashuntinpreterminfantsanarrativereview
AT amneetsidhu shouldweeliminatepdashuntinpreterminfantsanarrativereview
AT josephyting shouldweeliminatepdashuntinpreterminfantsanarrativereview