Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus
Background: Gynecomastia during adolescence is common though etiology is not clear. We studied the clinical and hormonal profile of adolescent patients with gynecomastia. Methodology: Patients who had onset of breast development between age 10 and 20 years were included in this study. Their clinical...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=1;spage=160;epage=164;aulast=Kulshreshtha |
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| author | Bindu Kulshreshtha Arora Arpita Patnaik T Rajesh Bhattacharya Sameek Deep Dutta Sharma Neera Mohsin Mohd |
| author_facet | Bindu Kulshreshtha Arora Arpita Patnaik T Rajesh Bhattacharya Sameek Deep Dutta Sharma Neera Mohsin Mohd |
| author_sort | Bindu Kulshreshtha |
| collection | DOAJ |
| description | Background: Gynecomastia during adolescence is common though etiology is not clear. We studied the clinical and hormonal profile of adolescent patients with gynecomastia. Methodology: Patients who had onset of breast development between age 10 and 20 years were included in this study. Their clinical profile, biochemical, and hormonal parameters were studied. Results: Of 94 patients with gynecomastia, 4 had hypogonadotropic hypogonadism, 4 had hypergonadotropic hypogonadism, and 1 had fibroadenosis, but in majority (90.4%), no apparent cause for breast enlargement was evident. In the idiopathic group, majority were obese (63%). Fourteen (16%) patients had impaired fasting glucose or impaired glucose tolerance. Another twenty patients had subtle abnormalities (high 1 h glucose or glucose peak at 2 h). Twenty-nine percent of lean and 38% of obese patients had mild abnormalities in glucose profile. Sixty percent of patients had family background of diabetes. Obese patients had lower testosterone as compared to lean patients; however, estradiol, luteinizing hormone, and follicle-stimulating hormone levels were similar in the two groups. Conclusion: Gynecomastia during adolescence is associated with obesity, dysglycemia, and family background of diabetes mellitus. |
| first_indexed | 2024-12-23T10:50:52Z |
| format | Article |
| id | doaj.art-07427c3ce86046bfbdedd2a3725917b3 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-12-23T10:50:52Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-07427c3ce86046bfbdedd2a3725917b32022-12-21T17:49:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102017-01-0121116016410.4103/2230-8210.196022Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitusBindu KulshreshthaArora ArpitaPatnaik T RajeshBhattacharya SameekDeep DuttaSharma NeeraMohsin MohdBackground: Gynecomastia during adolescence is common though etiology is not clear. We studied the clinical and hormonal profile of adolescent patients with gynecomastia. Methodology: Patients who had onset of breast development between age 10 and 20 years were included in this study. Their clinical profile, biochemical, and hormonal parameters were studied. Results: Of 94 patients with gynecomastia, 4 had hypogonadotropic hypogonadism, 4 had hypergonadotropic hypogonadism, and 1 had fibroadenosis, but in majority (90.4%), no apparent cause for breast enlargement was evident. In the idiopathic group, majority were obese (63%). Fourteen (16%) patients had impaired fasting glucose or impaired glucose tolerance. Another twenty patients had subtle abnormalities (high 1 h glucose or glucose peak at 2 h). Twenty-nine percent of lean and 38% of obese patients had mild abnormalities in glucose profile. Sixty percent of patients had family background of diabetes. Obese patients had lower testosterone as compared to lean patients; however, estradiol, luteinizing hormone, and follicle-stimulating hormone levels were similar in the two groups. Conclusion: Gynecomastia during adolescence is associated with obesity, dysglycemia, and family background of diabetes mellitus.http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=1;spage=160;epage=164;aulast=KulshreshthaAdolescentdiabetes mellitusdysglycemiagynecomastiaobesity |
| spellingShingle | Bindu Kulshreshtha Arora Arpita Patnaik T Rajesh Bhattacharya Sameek Deep Dutta Sharma Neera Mohsin Mohd Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus Indian Journal of Endocrinology and Metabolism Adolescent diabetes mellitus dysglycemia gynecomastia obesity |
| title | Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus |
| title_full | Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus |
| title_fullStr | Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus |
| title_full_unstemmed | Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus |
| title_short | Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus |
| title_sort | adolescent gynecomastia is associated with a high incidence of obesity dysglycemia and family background of diabetes mellitus |
| topic | Adolescent diabetes mellitus dysglycemia gynecomastia obesity |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2017;volume=21;issue=1;spage=160;epage=164;aulast=Kulshreshtha |
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