Dual role of Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice

Dual role of Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice

Arthritis in mice infected with the Lyme disease spirochete, Borrelia burgdorferi, results from the influx of innate immune cells responding to the pathogen in the joint and is influenced in part by mouse genetics. Production of inflammatory cytokines by innate immune cells in vitro is largely medi...

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Bibliographic Details
Main Authors: Alexia Anne Belperron, Nengyin eLiu, Carmen Jane Booth, Linda Kathryn Bockenstedt
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Arthritis
Borrelia burgdorferi
Lyme Disease
Mice
Toll-Like Receptors
MyD88
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00075/full

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