Knockdown resistance mutations are common and widely distributed in Xenopsylla cheopis fleas that transmit plague in Madagascar.

<h4>Background</h4>Plague, caused by the bacterium Yersinia pestis, remains an important disease in Madagascar, where the oriental rat flea, Xenopsylla cheopis, is a primary vector. To control fleas, synthetic pyrethroids (SPs) have been used for >20 years, resulting in resistance in...

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Bibliographic Details
Main Authors: Shelby M Hutton, Adelaide Miarinjara, Nathan E Stone, Fara N Raharimalala, Annick O Raveloson, Ravo Rakotobe Harimanana, Mireille Harimalala, Soanandrasana Rahelinirina, Ryelan F McDonough, Abbe D Ames, Crystal Hepp, Minoarisoa Rajerison, Joseph D Busch, David M Wagner, Romain Girod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011401