Sodium zirconium cyclosilicate and metabolic acidosis: Potential mechanisms and clinical consequences

Sodium zirconium cyclosilicate and metabolic acidosis: Potential mechanisms and clinical consequences

Metabolic acidosis is frequent in chronic kidney disease (CKD) and is associated with accelerated progression of CKD, hypercatabolism, bone disease, hyperkalemia, and mortality. Clinical guidelines recommend a target serum bicarbonate ≥ 22 mmol/L, but metabolic acidosis frequently remains undiagnose...

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Bibliographic Details
Main Authors: Raul Fernandez-Prado, Priscila Villalvazo, Alejandro Avello, Marina Gonzalez-de-Rivera, Michelle Aguirre, Carlos G. Carrasco-Muñoz, Beatriz Fernandez-Fernandez, Catalina Martin-Cleary, Sol Carriazo, Maria Dolores Sanchez-Niño, Maria Vanessa Perez-Gomez, Alberto Ortiz
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Chronic kidney disease
Veverimer
Sodium bicarbonate
Hyperkalemia
Carbamylation
Urea
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015864

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http://www.sciencedirect.com/science/article/pii/S0753332222015864

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