Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.853300/full |
| _version_ | 1818539850080452608 |
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| author | Ming Zheng Ming Zheng |
| author_facet | Ming Zheng Ming Zheng |
| author_sort | Ming Zheng |
| collection | DOAJ |
| first_indexed | 2024-12-11T21:47:33Z |
| format | Article |
| id | doaj.art-0746c1afb34840208bd34503b4e7f667 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-11T21:47:33Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-0746c1afb34840208bd34503b4e7f6672022-12-22T00:49:33ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-06-011310.3389/fimmu.2022.853300853300Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal ImplicationsMing Zheng0Ming Zheng1Institute of Military Cognition and Brain Sciences, Academy of Military Medical Sciences, Beijing, ChinaBeijing Institute of Basic Medical Sciences, Beijing, Chinahttps://www.frontiersin.org/articles/10.3389/fimmu.2022.853300/fullimmune checkpoint blockade (ICB)tumor mutation burden (TMB)hazard ratio (HR)human canceroverall survival (OS)cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) |
| spellingShingle | Ming Zheng Ming Zheng Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications Frontiers in Immunology immune checkpoint blockade (ICB) tumor mutation burden (TMB) hazard ratio (HR) human cancer overall survival (OS) cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) |
| title | Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications |
| title_full | Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications |
| title_fullStr | Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications |
| title_full_unstemmed | Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications |
| title_short | Dose-Dependent Effect of Tumor Mutation Burden on Cancer Prognosis Following Immune Checkpoint Blockade: Causal Implications |
| title_sort | dose dependent effect of tumor mutation burden on cancer prognosis following immune checkpoint blockade causal implications |
| topic | immune checkpoint blockade (ICB) tumor mutation burden (TMB) hazard ratio (HR) human cancer overall survival (OS) cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.853300/full |
| work_keys_str_mv | AT mingzheng dosedependenteffectoftumormutationburdenoncancerprognosisfollowingimmunecheckpointblockadecausalimplications AT mingzheng dosedependenteffectoftumormutationburdenoncancerprognosisfollowingimmunecheckpointblockadecausalimplications |