Isolation of nanobodies against Xenopus embryonic antigens using immune and non-immune phage display libraries.
The use of Xenopus laevis as a model for vertebrate developmental biology is limited by a lack of antibodies specific for embryonic antigens. This study evaluated the use of immune and non-immune phage display libraries for the isolation of single domain antibodies, or nanobodies, with specificities...
Main Authors: | Keiji Itoh, Alice H Reis, Andrew Hayhurst, Sergei Y Sokol |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0216083 |
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