Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR

Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrat...

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Main Authors: Sebastian Ludwig, MD, Daniel Kalbacher, MD, Lara Waldschmidt, MD, Andreas Schaefer, MD, MHBA, MD, Thomas Modine, MD, PhD, Danny Dvir, MD, Shemy Carasso, MD, Paolo Denti, MD, Niklas Schofer, MD, Lenard Conradi, MD
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:JACC: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266608492300178X
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author Sebastian Ludwig, MD
Daniel Kalbacher, MD
Lara Waldschmidt, MD
Andreas Schaefer, MD, MHBA, MD
Thomas Modine, MD, PhD
Danny Dvir, MD
Shemy Carasso, MD
Paolo Denti, MD
Niklas Schofer, MD
Lenard Conradi, MD
author_facet Sebastian Ludwig, MD
Daniel Kalbacher, MD
Lara Waldschmidt, MD
Andreas Schaefer, MD, MHBA, MD
Thomas Modine, MD, PhD
Danny Dvir, MD
Shemy Carasso, MD
Paolo Denti, MD
Niklas Schofer, MD
Lenard Conradi, MD
author_sort Sebastian Ludwig, MD
collection DOAJ
description Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)
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spelling doaj.art-074828f389f14917b6ac039a3469f9e02023-05-12T04:17:09ZengElsevierJACC: Case Reports2666-08492023-06-0116101873Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVRSebastian Ludwig, MD0Daniel Kalbacher, MD1Lara Waldschmidt, MD2Andreas Schaefer, MD, MHBA, MD3Thomas Modine, MD, PhD4Danny Dvir, MD5Shemy Carasso, MD6Paolo Denti, MD7Niklas Schofer, MD8Lenard Conradi, MD9Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Cardiovascular Research Foundation, New York, New York, USADepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, GermanyDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, GermanyGerman Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Department of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Hamburg, GermanyUnité Médico Chirurgicale de Valvulopathie, CHU de Bordeaux, Bordeaux, FranceDepartment of Cardiology, Shaare Zedek Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Cardiology, Shaare Zedek Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Cardiac Surgery, Ospedale San Raffaele, Milan, ItalyDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, GermanyGerman Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany; Department of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Hamburg, Germany; Address for correspondence: Dr Lenard Conradi, Department of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, D-20246 Hamburg, Germany.Left ventricular outflow tract obstruction represents a life-threatening complication in patients undergoing transcatheter mitral valve replacement. Interventional approaches to prevent left ventricular outflow tract obstruction are complex and require exceptional procedural expertise. We demonstrate feasibility and safety of first-in-human device-mediated mechanical laceration of the anterior mitral valve leaflet prior to transapical transcatheter mitral valve replacement. (Level of Difficulty: Advanced.)http://www.sciencedirect.com/science/article/pii/S266608492300178Xleaflet lacerationLVOT obstructiontranscatheter mitral valve replacement
spellingShingle Sebastian Ludwig, MD
Daniel Kalbacher, MD
Lara Waldschmidt, MD
Andreas Schaefer, MD, MHBA, MD
Thomas Modine, MD, PhD
Danny Dvir, MD
Shemy Carasso, MD
Paolo Denti, MD
Niklas Schofer, MD
Lenard Conradi, MD
Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
JACC: Case Reports
leaflet laceration
LVOT obstruction
transcatheter mitral valve replacement
title Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
title_full Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
title_fullStr Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
title_full_unstemmed Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
title_short Prevention of LVOT Obstruction by Device-Mediated Laceration of the Anterior Mitral Valve Leaflet During TMVR
title_sort prevention of lvot obstruction by device mediated laceration of the anterior mitral valve leaflet during tmvr
topic leaflet laceration
LVOT obstruction
transcatheter mitral valve replacement
url http://www.sciencedirect.com/science/article/pii/S266608492300178X
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