The Role of Imaging in Bladder Cancer Diagnosis and Staging

Bladder cancer (BC) is the most common cancer of the urinary tract in the United States. Imaging plays a significant role in the management of patients with BC, including the locoregional staging and evaluation for distant metastatic disease, which cannot be assessed at the time of cystoscopy and bi...

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Main Authors: Samuel J. Galgano, Kristin K. Porter, Constantine Burgan, Soroush Rais-Bahrami
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/9/703
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author Samuel J. Galgano
Kristin K. Porter
Constantine Burgan
Soroush Rais-Bahrami
author_facet Samuel J. Galgano
Kristin K. Porter
Constantine Burgan
Soroush Rais-Bahrami
author_sort Samuel J. Galgano
collection DOAJ
description Bladder cancer (BC) is the most common cancer of the urinary tract in the United States. Imaging plays a significant role in the management of patients with BC, including the locoregional staging and evaluation for distant metastatic disease, which cannot be assessed at the time of cystoscopy and biopsy/resection. We aim to review the current role of cross-sectional and molecular imaging modalities for the staging and restaging of BC and the potential advantages and limitations of each imaging modality. CT is the most widely available and frequently utilized imaging modality for BC and demonstrates good performance for the detection of nodal and visceral metastatic disease. MRI offers potential value for the locoregional staging and evaluation of muscular invasion of BC, which is critically important for prognostication and treatment decision-making. FDG-PET/MRI is a novel hybrid imaging modality combining the advantages of both MRI and FDG-PET/CT in a single-setting comprehensive staging examination and may represent the future of BC imaging evaluation.
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spelling doaj.art-074da056010c492e8e074b84e2c92ed02023-11-20T13:59:42ZengMDPI AGDiagnostics2075-44182020-09-0110970310.3390/diagnostics10090703The Role of Imaging in Bladder Cancer Diagnosis and StagingSamuel J. Galgano0Kristin K. Porter1Constantine Burgan2Soroush Rais-Bahrami3Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35249, USADepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35249, USADepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35249, USADepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35249, USABladder cancer (BC) is the most common cancer of the urinary tract in the United States. Imaging plays a significant role in the management of patients with BC, including the locoregional staging and evaluation for distant metastatic disease, which cannot be assessed at the time of cystoscopy and biopsy/resection. We aim to review the current role of cross-sectional and molecular imaging modalities for the staging and restaging of BC and the potential advantages and limitations of each imaging modality. CT is the most widely available and frequently utilized imaging modality for BC and demonstrates good performance for the detection of nodal and visceral metastatic disease. MRI offers potential value for the locoregional staging and evaluation of muscular invasion of BC, which is critically important for prognostication and treatment decision-making. FDG-PET/MRI is a novel hybrid imaging modality combining the advantages of both MRI and FDG-PET/CT in a single-setting comprehensive staging examination and may represent the future of BC imaging evaluation.https://www.mdpi.com/2075-4418/10/9/703urothelial carcinomamagnetic resonance imagingpositron emission tomographycomputed tomographycancer stagingmuscle-invasive bladder cancer
spellingShingle Samuel J. Galgano
Kristin K. Porter
Constantine Burgan
Soroush Rais-Bahrami
The Role of Imaging in Bladder Cancer Diagnosis and Staging
Diagnostics
urothelial carcinoma
magnetic resonance imaging
positron emission tomography
computed tomography
cancer staging
muscle-invasive bladder cancer
title The Role of Imaging in Bladder Cancer Diagnosis and Staging
title_full The Role of Imaging in Bladder Cancer Diagnosis and Staging
title_fullStr The Role of Imaging in Bladder Cancer Diagnosis and Staging
title_full_unstemmed The Role of Imaging in Bladder Cancer Diagnosis and Staging
title_short The Role of Imaging in Bladder Cancer Diagnosis and Staging
title_sort role of imaging in bladder cancer diagnosis and staging
topic urothelial carcinoma
magnetic resonance imaging
positron emission tomography
computed tomography
cancer staging
muscle-invasive bladder cancer
url https://www.mdpi.com/2075-4418/10/9/703
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