Covalent Modification of Human Serum Albumin by the Natural Sesquiterpene Lactone Parthenolide

Covalent Modification of Human Serum Albumin by the Natural Sesquiterpene Lactone Parthenolide

The reactivity of parthenolide (PRT), a natural sesquiterpene lactone from Tanacetum parthenium (Asteraceae), with human serum albumin (HSA) was studied by UHPLC/+ESI-QqTOF MS analysis after tryptic digestion of albumin samples after incubation with this compound. It was found that the single free c...

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Bibliographic Details
Main Authors: Michael Plöger, Jandirk Sendker, Klaus Langer, Thomas J. Schmidt
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
sesquiterpene lactone
parthenolide
human serum albumin
tryptic digest
UHPLC/+ESI-QqTOF MS
Online Access:http://www.mdpi.com/1420-3049/20/4/6211

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