Optimizing drug combination and mechanism analysis based on risk pathway crosstalk in pan cancer
Abstract Combination therapy can greatly improve the efficacy of cancer treatment, so identifying the most effective drug combination and interaction can accelerate the development of combination therapy. Here we developed a computational network biological approach to identify the effective drug wh...
Main Authors: | Congxue Hu, Wanqi Mi, Feng Li, Lun Zhu, Qi Ou, Maohao Li, Tengyue Li, Yuheng Ma, Yunpeng Zhang, Yingqi Xu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Scientific Data |
Online Access: | https://doi.org/10.1038/s41597-024-02915-y |
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