Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan

From January 2019 to May 2021, 11 children underwent allogeneic stem cell transplantation at our institute. Four of them received letermovir for cytomegalovirus prophylaxis. Three children, none of whom received prophylaxis, experienced cytomegalovirus reactivation. Letermovir is a promising medicat...

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Main Authors: Chao-Neng Cheng, Sin-Syue Li, Yun-Hsuan Yeh, Ching-Fen Shen, Jiann-Shiuh Chen
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118222000184
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author Chao-Neng Cheng
Sin-Syue Li
Yun-Hsuan Yeh
Ching-Fen Shen
Jiann-Shiuh Chen
author_facet Chao-Neng Cheng
Sin-Syue Li
Yun-Hsuan Yeh
Ching-Fen Shen
Jiann-Shiuh Chen
author_sort Chao-Neng Cheng
collection DOAJ
description From January 2019 to May 2021, 11 children underwent allogeneic stem cell transplantation at our institute. Four of them received letermovir for cytomegalovirus prophylaxis. Three children, none of whom received prophylaxis, experienced cytomegalovirus reactivation. Letermovir is a promising medication for use in cytomegalovirus prophylaxis in children. Further studies are warranted.
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spelling doaj.art-0754ae26951f4819a523117258d0da842022-12-22T00:14:10ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822022-04-01552323327Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in TaiwanChao-Neng Cheng0Sin-Syue Li1Yun-Hsuan Yeh2Ching-Fen Shen3Jiann-Shiuh Chen4Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Corresponding author. Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138, Sheng-Li Rd, Tainan, 70403, Taiwan. Fax: +886 6 2753083.From January 2019 to May 2021, 11 children underwent allogeneic stem cell transplantation at our institute. Four of them received letermovir for cytomegalovirus prophylaxis. Three children, none of whom received prophylaxis, experienced cytomegalovirus reactivation. Letermovir is a promising medication for use in cytomegalovirus prophylaxis in children. Further studies are warranted.http://www.sciencedirect.com/science/article/pii/S1684118222000184ChildrenCytomegalovirusHematopoietic stem cell transplantationLetermovirProphylaxis
spellingShingle Chao-Neng Cheng
Sin-Syue Li
Yun-Hsuan Yeh
Ching-Fen Shen
Jiann-Shiuh Chen
Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
Journal of Microbiology, Immunology and Infection
Children
Cytomegalovirus
Hematopoietic stem cell transplantation
Letermovir
Prophylaxis
title Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
title_full Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
title_fullStr Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
title_full_unstemmed Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
title_short Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan
title_sort letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation a single institute experience in taiwan
topic Children
Cytomegalovirus
Hematopoietic stem cell transplantation
Letermovir
Prophylaxis
url http://www.sciencedirect.com/science/article/pii/S1684118222000184
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