Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview

Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview

The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is widely expressed in the central and peripheral nervous systems. This receptor is implicated in both brain development and adult neurogenesis thanks to its ability to mediate acetylcholine stimulus (Ach). Copy number variations (...

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Bibliographic Details
Main Authors: Angela Maria Giada Giovenale, Giorgia Ruotolo, Amata Amy Soriano, Elisa Maria Turco, Giovannina Rotundo, Alessia Casamassa, Angela D’Anzi, Angelo Luigi Vescovi, Jessica Rosati
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neurodevelopmental disorders
neuropsychiatric disorders
15q11-13
CHRNA7
nicotinic acetylcholine receptor
copy number variation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1107881/full

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