The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis
Abstract Background This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. Methods Studies that investigated the survival rate of kidney transplants published until the 30th of December...
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12887-022-03545-2 |
| _version_ | 1828121763091841024 |
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| author | Mousa Ghelichi-Ghojogh Fateme Mohammadizadeh Fatemeh Jafari Mouhebat Vali Sepideh Jahanian Masoud Mohammadi Alireza Jafari Rozhan Khezri Hossein-Ali Nikbakht Masumeh Daliri Abdolhalim Rajabi |
| author_facet | Mousa Ghelichi-Ghojogh Fateme Mohammadizadeh Fatemeh Jafari Mouhebat Vali Sepideh Jahanian Masoud Mohammadi Alireza Jafari Rozhan Khezri Hossein-Ali Nikbakht Masumeh Daliri Abdolhalim Rajabi |
| author_sort | Mousa Ghelichi-Ghojogh |
| collection | DOAJ |
| description | Abstract Background This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. Methods Studies that investigated the survival rate of kidney transplants published until the 30th of December 2020 were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane. The extracted data were entered into the Excel software and STATA 16.0. The search identified 6007 study references. From the total, we excluded 1348 duplicates, 3688 reference titles and abstracts that were deemed irrelevant, and 846 references that were not original articles (i.e., letter, commentary, review) or did not meet the inclusion criteria. As such, 89 studies involving 12,330 participants were included in this meta-analysis. Results In this study 1, 3, 5, 7 and 10-year survival rates of graft were estimated to be 92, 83, 74.40, 67.10, and 63.50%, respectively. Also, 1, 3, 5, 7 and 10-year survival rates of patients were estimated to be 99.60, 97.30, 95.20, 74.60, and 97.90%, respectively. Conclusions The findings suggest differences in graft and patient survival among children with kidney transplants. Although differences in ethnic origin, incompatibility with deceased donor kidneys, and types of kidney disease are unavoidable, interventions to improve preventive and living-donor transplantation are particularly needed in minority groups. In addition, more research is needed to establish and address the contribution of medical and sociocultural barriers to preferential treatment of these groups. |
| first_indexed | 2024-04-11T14:25:05Z |
| format | Article |
| id | doaj.art-0757f74159fe4d68b35b9f212c9da6cc |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-11T14:25:05Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-0757f74159fe4d68b35b9f212c9da6cc2022-12-22T04:18:54ZengBMCBMC Pediatrics1471-24312022-08-0122111510.1186/s12887-022-03545-2The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysisMousa Ghelichi-Ghojogh0Fateme Mohammadizadeh1Fatemeh Jafari2Mouhebat Vali3Sepideh Jahanian4Masoud Mohammadi5Alireza Jafari6Rozhan Khezri7Hossein-Ali Nikbakht8Masumeh Daliri9Abdolhalim Rajabi10Health Management and Social Development Research Center, Faculty of Health, Golestan University of Medical SciencesDepartment of Epidemiology, Shiraz University of Medical SciencesDepartment of Epidemiology, Shiraz University of Medical SciencesDepartment of Epidemiology, Shiraz University of Medical SciencesDepartment of Cardiovascular Surgery, Mayo Clinic, College of Medicine and ScienceResearch Center of Gastroenterology and Hepatology, Golestan University of Medical SciencesDepartment of Health Education and Health Promotion, School of Health, Social Development and Health Promotion Research Center, Gonabad University of Medical SciencesUrmia Health center, Urmia University of Medical SciencesSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical SciencesDepartment of Epidemiology, Shiraz University of Medical SciencesHealth Management and Social Development Research Center, Faculty of Health, Golestan University of Medical SciencesAbstract Background This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. Methods Studies that investigated the survival rate of kidney transplants published until the 30th of December 2020 were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane. The extracted data were entered into the Excel software and STATA 16.0. The search identified 6007 study references. From the total, we excluded 1348 duplicates, 3688 reference titles and abstracts that were deemed irrelevant, and 846 references that were not original articles (i.e., letter, commentary, review) or did not meet the inclusion criteria. As such, 89 studies involving 12,330 participants were included in this meta-analysis. Results In this study 1, 3, 5, 7 and 10-year survival rates of graft were estimated to be 92, 83, 74.40, 67.10, and 63.50%, respectively. Also, 1, 3, 5, 7 and 10-year survival rates of patients were estimated to be 99.60, 97.30, 95.20, 74.60, and 97.90%, respectively. Conclusions The findings suggest differences in graft and patient survival among children with kidney transplants. Although differences in ethnic origin, incompatibility with deceased donor kidneys, and types of kidney disease are unavoidable, interventions to improve preventive and living-donor transplantation are particularly needed in minority groups. In addition, more research is needed to establish and address the contribution of medical and sociocultural barriers to preferential treatment of these groups.https://doi.org/10.1186/s12887-022-03545-2Kidney transplantationGraft survivalPatient survivalMeta-analysis |
| spellingShingle | Mousa Ghelichi-Ghojogh Fateme Mohammadizadeh Fatemeh Jafari Mouhebat Vali Sepideh Jahanian Masoud Mohammadi Alireza Jafari Rozhan Khezri Hossein-Ali Nikbakht Masumeh Daliri Abdolhalim Rajabi The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis BMC Pediatrics Kidney transplantation Graft survival Patient survival Meta-analysis |
| title | The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis |
| title_full | The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis |
| title_fullStr | The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis |
| title_full_unstemmed | The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis |
| title_short | The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis |
| title_sort | global survival rate of graft and patient in kidney transplantation of children a systematic review and meta analysis |
| topic | Kidney transplantation Graft survival Patient survival Meta-analysis |
| url | https://doi.org/10.1186/s12887-022-03545-2 |
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