Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features

Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features

<i>Background:</i> Hypoxia is recognized as a key feature of cancer growth and is involved in various cellular processes, including proliferation, angiogenesis, and immune surveillance. Besides hypoxia-inducible factor 1-alpha (HIF-1α), which is the main mediator of hypoxia effects and c...

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Main Authors: Panagiotis J. Vlachostergios, Ioannis A. Tamposis, Maria Anagnostou, Maria Papathanassiou, Lampros Mitrakas, Ioannis Zachos, Eleni Thodou, Maria Samara, Vassilios Tzortzis
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Current Oncology
Subjects:
hypoxia-inducible factor 2
<i>EPAS1</i>
urothelial carcinoma
bladder cancer
genomic landscape
prognosis
Online Access:https://www.mdpi.com/1718-7729/29/11/681

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