Neural correlates of enhanced response inhibition in the aftermath of stress
Life stress has been shown to impact cognitive functions, including inhibitory control. However, the immediate effects of acute stress on inhibitory control and the underlying neural mechanisms remain unclear. In a behavioral pilot study (N = 30) and a within-subject functional magnetic resonance im...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811919308031 |
| _version_ | 1818508439377149952 |
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| author | Jingjing Chang Jianping Hu Chiang-Shan R. Li Rongjun Yu |
| author_facet | Jingjing Chang Jianping Hu Chiang-Shan R. Li Rongjun Yu |
| author_sort | Jingjing Chang |
| collection | DOAJ |
| description | Life stress has been shown to impact cognitive functions, including inhibitory control. However, the immediate effects of acute stress on inhibitory control and the underlying neural mechanisms remain unclear. In a behavioral pilot study (N = 30) and a within-subject functional magnetic resonance imaging study (N = 30), we examined how acute stress induced by Trier Social Stress Test influenced inhibitory control in a stop signal task. Behavioral results across two studies showed that stress consistently improved inhibitory control. Shorter stop signal reaction time (SSRT) in stress as compared with control condition was associated with stronger connectivity between the superior/middle frontal gyrus (SFG/MFG) and striatum. Dynamic causal modeling revealed distinct best models under stress and control condition, with an enhanced interaction between the SFG/MFG and the striatum after stress exposure. This research identified the SFG/MFG-striatum network as a key circuit underlying acute stress-elicited enhancement of inhibitory control in a stop signal task. |
| first_indexed | 2024-12-10T22:31:54Z |
| format | Article |
| id | doaj.art-075bc3351eb046358d44cfb7038f0044 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-10T22:31:54Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-075bc3351eb046358d44cfb7038f00442022-12-22T01:31:02ZengElsevierNeuroImage1095-95722020-01-01204116212Neural correlates of enhanced response inhibition in the aftermath of stressJingjing Chang0Jianping Hu1Chiang-Shan R. Li2Rongjun Yu3Guangdong Key Laboratory of Mental Health and Cognitive Science, Center for Studies of Psychological Application, School of Psychology, South China Normal University, Guangzhou, ChinaLaboratory for Behavioral and Regional Finance, Guangdong University of Finance, Guangzhou, ChinaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USADepartment of Psychology, National University of Singapore, Singapore; Corresponding author. Department of Psychology, National University of Singapore, 117570, Singapore.Life stress has been shown to impact cognitive functions, including inhibitory control. However, the immediate effects of acute stress on inhibitory control and the underlying neural mechanisms remain unclear. In a behavioral pilot study (N = 30) and a within-subject functional magnetic resonance imaging study (N = 30), we examined how acute stress induced by Trier Social Stress Test influenced inhibitory control in a stop signal task. Behavioral results across two studies showed that stress consistently improved inhibitory control. Shorter stop signal reaction time (SSRT) in stress as compared with control condition was associated with stronger connectivity between the superior/middle frontal gyrus (SFG/MFG) and striatum. Dynamic causal modeling revealed distinct best models under stress and control condition, with an enhanced interaction between the SFG/MFG and the striatum after stress exposure. This research identified the SFG/MFG-striatum network as a key circuit underlying acute stress-elicited enhancement of inhibitory control in a stop signal task.http://www.sciencedirect.com/science/article/pii/S1053811919308031StressStop signal taskResponse inhibitionStriatumPrefrontal cortex |
| spellingShingle | Jingjing Chang Jianping Hu Chiang-Shan R. Li Rongjun Yu Neural correlates of enhanced response inhibition in the aftermath of stress NeuroImage Stress Stop signal task Response inhibition Striatum Prefrontal cortex |
| title | Neural correlates of enhanced response inhibition in the aftermath of stress |
| title_full | Neural correlates of enhanced response inhibition in the aftermath of stress |
| title_fullStr | Neural correlates of enhanced response inhibition in the aftermath of stress |
| title_full_unstemmed | Neural correlates of enhanced response inhibition in the aftermath of stress |
| title_short | Neural correlates of enhanced response inhibition in the aftermath of stress |
| title_sort | neural correlates of enhanced response inhibition in the aftermath of stress |
| topic | Stress Stop signal task Response inhibition Striatum Prefrontal cortex |
| url | http://www.sciencedirect.com/science/article/pii/S1053811919308031 |
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