Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices
Aortic regurgitation (AR) is not the most common valvular disease; however, its prevalence increases with age, with more than 2% of those aged >70 years having at least moderate AR. Once symptoms related to AR develop, the prognosis becomes poor. Transcatheter aortic valve implantation for patien...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2022-07-01
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| Series: | Interventional Cardiology: Reviews, Research, Resources |
| Online Access: | https://www.icrjournal.com/articleindex/icr.2021.19 |
| _version_ | 1797199958369107968 |
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| author | Pierluigi Costanzo Paul Bamborough Mark Peterson Djeven J Deva Geraldine Ong Neil Fam |
| author_facet | Pierluigi Costanzo Paul Bamborough Mark Peterson Djeven J Deva Geraldine Ong Neil Fam |
| author_sort | Pierluigi Costanzo |
| collection | DOAJ |
| description | Aortic regurgitation (AR) is not the most common valvular disease; however, its prevalence increases with age, with more than 2% of those aged >70 years having at least moderate AR. Once symptoms related to AR develop, the prognosis becomes poor. Transcatheter aortic valve implantation for patients with pure severe AR and at prohibitive surgical risk is occasionally performed, but remains a clinical challenge due to absence of valvular calcium, large aortic root and increased stroke volume. These issues make the positioning and deployment of transcatheter aortic valve implantation devices unpredictable, with a tendency to prosthesis embolisation or malposition. To date, the only two dedicated transcatheter valves for AR are the J-Valve (JC Medical) and the JenaValve (JenaValve Technology). Both devices have been used successfully via the transapical approach. The transfemoral experience is limited to first-in-human publications and to a clinical trial dedicated to AR, for which the completion date is still pending. |
| first_indexed | 2024-03-07T17:39:35Z |
| format | Article |
| id | doaj.art-075d8b882182474bbe1326de3bebb82d |
| institution | Directory Open Access Journal |
| issn | 1756-1477 1756-1485 |
| language | English |
| last_indexed | 2024-04-24T07:24:01Z |
| publishDate | 2022-07-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Interventional Cardiology: Reviews, Research, Resources |
| spelling | doaj.art-075d8b882182474bbe1326de3bebb82d2024-04-20T16:02:58ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852022-07-011710.15420/icr.2021.19Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated DevicesPierluigi Costanzo0Paul Bamborough1Mark Peterson2Djeven J Deva3Geraldine Ong4Neil Fam5Division of Cardiology, St Michael’s Hospital, University of Toronto, Toronto, Canada; Division of Cardiology, Royal Papworth Hospital, Cambridge, UKDivision of Cardiology, Royal Papworth Hospital, Cambridge, UKDivision of Cardiac Surgery, St Michael’s Hospital, University of Toronto, Toronto, CanadaDepartment of Medical Imaging, St Michael’s Hospital, University of Toronto, Toronto, CanadaDivision of Cardiology, St Michael’s Hospital, University of Toronto, Toronto, CanadaDivision of Cardiology, St Michael’s Hospital, University of Toronto, Toronto, CanadaAortic regurgitation (AR) is not the most common valvular disease; however, its prevalence increases with age, with more than 2% of those aged >70 years having at least moderate AR. Once symptoms related to AR develop, the prognosis becomes poor. Transcatheter aortic valve implantation for patients with pure severe AR and at prohibitive surgical risk is occasionally performed, but remains a clinical challenge due to absence of valvular calcium, large aortic root and increased stroke volume. These issues make the positioning and deployment of transcatheter aortic valve implantation devices unpredictable, with a tendency to prosthesis embolisation or malposition. To date, the only two dedicated transcatheter valves for AR are the J-Valve (JC Medical) and the JenaValve (JenaValve Technology). Both devices have been used successfully via the transapical approach. The transfemoral experience is limited to first-in-human publications and to a clinical trial dedicated to AR, for which the completion date is still pending.https://www.icrjournal.com/articleindex/icr.2021.19 |
| spellingShingle | Pierluigi Costanzo Paul Bamborough Mark Peterson Djeven J Deva Geraldine Ong Neil Fam Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices Interventional Cardiology: Reviews, Research, Resources |
| title | Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices |
| title_full | Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices |
| title_fullStr | Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices |
| title_full_unstemmed | Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices |
| title_short | Transcatheter Aortic Valve Implantation for Severe Pure Aortic Regurgitation with Dedicated Devices |
| title_sort | transcatheter aortic valve implantation for severe pure aortic regurgitation with dedicated devices |
| url | https://www.icrjournal.com/articleindex/icr.2021.19 |
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